Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"UCL Cancer Institute"”.
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Combination therapy studies with the vascular disruptive agent combretastatin-a4-phosphate (CA4P)
CA4P leads to rapid vascular shutdown of tumour core, with minimal effects at the well perfused periphery. CA4P showed minimal anti-tumour activity in single agent phase I studies. This thesis examined the feasibility of CA4P combination therapy, examining the hypothesis that two agents may be …