Global ETD Search
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Showing 1 to 5 of 5 for “"U2-U6"”.
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Single Molecule Studies Of Spliceosomal Snrnas U2-U6
… core comprises three small nuclear RNAs (U2, U5</p> <p>and U6) involved in substrate positioning and catalysis. It has been postulated, but never</p> <p>shown experimentally, that the U2-U6 complex adopts at least two conformations that</p> <p>reflect different activation states. We have …
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Conformational features of the human U2-U6 snRNA complex
… aspects of the process. A complex formed between U2 and U6 snRNAs is implicated in the chemistry of pre-mRNA splicing. The catalytic activity of the U2-U6 snRNA complex is dependent on the presence of Mg2+ ions, and the complex has been shown to have several specifically bound Mg2+ binding sites …
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Conformation of the U12-U6atac snRNA Complex of the Minor Spliceosome and Binding by NTC-related Protein RBM22
… of small nuclear (sn)RNA-protein complexes (U1, U2, U4, U5 and U6) and >100 proteins. snRNA components catalyze the two transesterification reactions while proteins perform critical roles in assembly and rearrangement. U2 and U6 snRNAs are the only snRNAs directly implicated in catalyzing the …
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Characterization of splicing mechanisms by single-molecule fluorescence
… Out of five snRNAs, only the highly conserved U2 and U6 snRNAs are required in both steps of RNA splicing. The U2-U6 snRNA complex forms the active site of the spliceosome and has been shown to undergo splicing-related catalysis in the absence of proteins. Single-molecule studies of yeast U2-U6 …
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The Impacts of Acid Mine Drainage on the Black Creek Watershed, Wise County, Virginia
… results indicating little impairment. Stations U2, U6, U7, and BBM were also found to be Slightly Impaired. The station on the margin of the wetland, U5, was Moderately Impaired. Two previously identified areas of impairment, U9 and U10, (Cherry et al. 1995) were identified as Severely pH …