Global ETD Search
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Showing 1 to 1 of 1 for “"Tysiponate"”.
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Development of Immune Modulators Targeting Autoimmune Disorders and Pulmonary Injury: Design, Synthesis, and Biological Evaluation of Sphingolipid-Derived Sphingosine-1 Phosphate Receptor 1 Agonists
… The lead compound is a fingolimod derivative – tysiponate – which avoids the drawbacks of prodrug nature and low cellular stability and bioavailability the conventional drug on the market features. The compound has been synthesized in a conventional, linear fashion, as well as in a novel, …