Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Type II restriction enzymes"”.
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Development and applications of programmable DNA-guided Argonaute-based artificial restriction enzymes
Restriction enzymes or formally known as restriction endonucleases are a class of nuclease enzymes which recognize short DNA sequences and cleave DNA molecules at or near their recognition site. Type II restriction enzymes are capable of cleavage of DNA at a fixed location with respect to their …
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Learning hierarchical motif embeddings for protein engineering
… model on the DNA recognition code of the Type II restriction enzymes. Based on the promising prediction results, we used the trained models to generate de novo restriction enzymes and paved the way towards the computational design of a restriction enzyme that will cut a given arbitrary DNA …
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A study of protein-DNA interactions using atomic force microscopy and DNA origami
… such as viruses invading a bacterium. Restriction enzymes defend the host bacteria by recognising specific sites on the viral DNA and cutting invading viruses at those sites. We aim first to understand how these proteins translocate along the viral DNA molecules toward their recognition …