Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 133 for “"Tweezers"”.
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Micro-led based optoelectronic tweezers
… a compact illumination source in optoelectronic tweezers systems is explored. The emerging technique of optoelectronic tweezers uses light patterns to generate electric field gradients to trap and manipulate single cells. Micro-LEDs offer an advantageous alternative to current illumination …
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Robot-assisted acoustic vortex tweezers
Acoustic tweezers are a widely used methodology to achieve contactless manipulation. By generating the acoustic potential well to harness the targeted objects, acoustic tweezers have shown significant potential in various biomedical and biochemical research fields. Compared to other mechanisms of …
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Assembly of Structures using Optical Tweezers
… and linking (OPAL) platform based on optical tweezers and a biochemical linking mechanism. Optical tweezers (OT) are a powerful technique that permit the non-contact manipulation of a range of objects, spanning from the nanoscale to the microscale for a variety of material compositions. OT …
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High Resolution Optical Tweezers for Biological Studies
… tool with such capabilities is an optical tweezers. Optical tweezers is a non-invasive all-optical technique in which typically a dielectric microsphere is held by a tightly focused laser beam. This microsphere acts like a microscopic, three-dimensional spring and is used as a handle to …
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Developing Magnetic Tweezers for Magnetic Material Manipulation
… Among current available methods, the magnetic tweezers show high efficiency and cost effectiveness in generating strong and direction adjustable interactions with magnetic materials. Since our research group has extensive experience in synthesizing magnetic nanostructures, it is of great …
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Optical tweezers for signal detection and micromanipulation
… new multi-disciplinary applications of optical tweezers in the physical and biological sciences. Firstly, the three dimensional trapping of partially silvered sphere in a standard TEM00 optical trap was characterised. These spheres were then coated with an azo dye such that surface-enhanced …
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High-speed video microscopy in optical tweezers
Optical tweezers have become an invaluable tool for measuring and exerting forces in the pico-Newton regime. Force measurements have in the past concentrated on using only one trapped particle as a probe, partly due to the difficulties in tracking more than one par- ticle at high enough frame rate. …
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Photonic Tweezers for Optical Manipulation of Cells and Tissues
Optical tweezers represent a powerful tool for studying forces in biological samples. In this thesis, I explored applications of optical tweezers that pushed the technique beyond its limitations. In fact I worked on extending the range of forces applicable by the tweezers and on applying optical …
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Molecular tweezers: Synthetic receptors for the DNA base adenine
The design and syntheses of a series of molecular tweezers containing functional groups in the bay area of the spacers are discussed. Molecular tweezers 98, 99, 120, and 128 were designed to complex the DNA base adenine through a combination of hydrogen bonding and $\pi$-stacking interactions. They …
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Tools to study the kinesin mechanome using optical tweezers
Molecular motors play an important role in driving some of the most complex and important tasks in biological systems, ranging from transcribing RNA from a DNA template (Polymerases) to muscle contraction (Myosin) and propelling bacteria (Flagellum). Key to the understanding of the fundamental …
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An automated and user-friendly optical tweezers for biomolecular investigations
Optical tweezers are not new to biological applications but building a tweezers which is versatile, automated, precise, stable and user-friendly is quite challenging. Such a tweezers usually require not only a hefty budget but vast understanding of engineer- ing of optomechanical systems. I …
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Membrane tether formation from outer hair cells with optical tweezers
… the mechanism of OHC electromotility. Optical tweezers were used to characterize the mechanical properties of OHC plasma membrane (PM) by pulling tethers. A greater force was required for tether formations from OHC lateral wall (499 pN +/- 152) than from OHC basal end (142 pN +/- 49), …
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Modeling and Experimental Techniques to Demonstrate Nanomanipulation With Optical Tweezers
… and improve the performance of optical tweezers at the nanoscale, but depend on accurate trapping force models. Therefore, we have also developed two new laboratory-based force measurement techniques that overcome the drawbacks of conventional force measurements, which do not accurately …
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Antibody-Antigen assay design for combined optical tweezers and fluorescence
The recent development in combined optical trapping and fluorescence technology promises to enable unbindinig force studies of receptor-ligand interactions, whose specificity play a crucial role in the function of many biological systems. This thesis focuses on the development of assay designs for …
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Exploring the mechanome with optical tweezers and single molecule fluorescence
The combination of optical tweezers and single molecule fluorescence into an instrument capable of making combined, coincident measurements adds an observable dimension that allows for the examination of the localized effects of applied forces on biological systems. This technological advance had …
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Optical tweezers using the Texas Instruments' Digital Micromirror Device(tm)
Thesis (M.Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2001.
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Ion flow and membrane tension studies with optical tweezers and nanopipettes
… setup and the studies this has enabled. Optical tweezers, nanopipettes, and fluorescence were all combined to study the effect of salt species on nanoscale voltage driven flows, the mechanical behaviour of cell membranes, and the electrical activity from various cells. Voltage driven, or …
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Probing DNA-Induced Colloidal Interactions and Dynamics with Scanning-Line Optical Tweezers
… energies measured with our optical tweezers instrument can be modeled quantitatively with a conceptually straightforward and numerically tractable model, boding well for their application to direct self-assembly. In addition to understanding the equilibrium interactions between …
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