Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Tumour Perfusion"”.
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Evaluation of tumour perfusion and fibrosis in mouse models of pancreatic ductal adenocarcinoma, using MRI
… features of human PDA. Spontaneous KPC tumours are also chemoresistant and this mouse model therefore provides an ideal platform from which to study the biology of PDA. Recent evidence suggests that poor perfusion and extensive fibrosis may prevent the delivery of cytotoxic agents to …
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Analyzing the Effect of Neoadjuvant Stereotactic Ablative Body Radiotherapy on Pancreatic Tumour Perfusion Using Computed Tomography Perfusion
… critical vessel structures around the primary tumour. Patients with limited but non-negligible involvement of the surrounding vasculature, known as borderline-resectable pancreatic cancer (BRPC) patients, often have poor surgical prognosis. Thus, to potentially reduce the tumour-vessel contact …
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The use of conventional and advanced magnetic resonance techniques in the assessment of primary brain tumours
… was to investigate the value of conventional, perfusion- and diffusion-weighted magnetic resonance imaging (MRI) in patients with histology-proven low-grade gliomas (LGG), and the potential role of these methods in the management of patients with these brain tumours. Thirty-six patients were …
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Functional imaging of cancer using Optoacoustic Tomography
Poor oxygenation of solid tumours has been linked with resistance to chemo- and radio-therapy and poor patient outcomes. Measuring the functional status of the tumour vasculature, including blood flow fluctuations and changes in oxygenation is important in cancer staging and therapy monitoring. A …
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Imaging Metabolic Signatures in High Grade Serous Ovarian Cancer
… cancer and has demonstrated inter and intra-tumoural metabolic heterogeneity, where metabolic differences were observed between patients and between different tumour deposits within the same patient. Here I compared the use of <sup>13</sup>C magnetic resonance spectroscopic imaging (MRSI) of …
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The analysis of dynamic contrast-enhanced magnetic resonance imaging data: treatment effects, sampling rates and repeatability
… which reflect the physiological properties of tumours. Historically, these analysis procedures have been complicated by varied sources of error, both systematic and random. This dissertation investigates improvements to such techniques and the hypothesised gain in accuracy when implementing a …