Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 2194 for “"Tumors"”.
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Tumors in Surgical Pathology
My purpose is to determine the tutors most frequently encountered tn the everyday practice of surgical pathology and compare the incidence with that reported in the standard pathology texts. I am primarily concerned with the availability of material for teaching oncology to graduate and medical …
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Lymphatic pathophysiology of tumors
… well understood. The universal finding in solid tumors of an absence of functional lymphatic vessels seems paradoxical, as cancer cells do travel through lymphatics in order to disseminate. In order to address some of these issues, this thesis proposes two etiologies for the absence of functional …
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Long term impact of endocrine tumors
Contains fulltext : 207771.pdf (Publisher’s version ) (Open Access)
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Scanned Ion Beam Therapy For Thoracic Tumors
<p>Although frequently cured of Hodgkin lymphoma, adolescents and young adults can develop radiation induced second cancers. These patients could potentially benefit from scanned ion radiotherapy yet likely would require motion mitigation strategies. In theory, four-dimensional (4D) optimization of …
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Cell Shapes Indicate Tissue Fluidity in Tumors
Die Tumorprogression wird von Veränderungen der Gewebemorphologie begleitet. In 2D-Zellkulturen wurden verschiedene Gewebezustände gefunden, z.B. flüssigar- tige, 'gejammete' sowie nematische Zustände, die mit den Zellformen zusammen- hingen. Obwohl man diese Resultate nicht einfach auf …
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Experimental brain tumors, dendritic cells and immunotherapy
… astrocytomas are the most common primary tumors of the adult central nervous system. Surgical resection of tumor mass in combination with radiotherapy and chemotherapy is only palliative and there is a clear need for new and more effective therapeutic strategies. The aim of this study was …
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Defining sources of nutrient limitation for tumors
… cells, and nutrient accessibility in tumors is different than in normal tissues. Thus, tumor survival and growth may be limited by different metabolic factors than those that are necessary to maintain non-cancerous cells. This dissertation examines sources of nutrient limitation in …
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Gallium-68 DOTATATE PET/CT in Neuroendocrine Tumors
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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T-Cell Treatments For Solid and Hematological Tumors
<p>Cell-based therapies have demonstrated potency and efficacy as cancer treatment modalities. T cells can be dichotomized by their T cell receptor (TCR) complexes where alpha/beta T cells (95% of T cells) and gamma/delta T cells (+T cells proliferated to clinically significant numbers and …
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Drug Delivery to Solid Tumors via Polymeric Nanoparticles
A main challenge in chemotherapy is to deliver an anti-cancer drug selectively to tumor and avoid off-target exposure to other body tissues and organs. Nanoparticles (NPs) have been considered a promising approach for tumor drug delivery, with popularity attributable to the famous “Enhanced …
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Mathematical Models of Tumors and Their Remote Metastases
… have led us to investigate several models of tumors. For example, it has been shown that a tumor has the ability to send out anti-growth factors, or inhibitors, to keep its remote metastases from growing. Thus, we model the depleting effect of such a growth inhibitor after the removal of the …
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Stem cell based therapy of malignant brain tumors
… NPCs and MSCs did not proliferate within tumors. This indicates a low risk of development of secondary malignancies. A comparative analysis revealed higher survival and better intratumoral migratory capacity of implanted MSCs, compared to NPCs. Intratumorally implanted MSCs migrated to the …
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Insulin-secreting tumors of the islets of Langerhans
Thesis (M.D.)—-Boston University
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Treatment of murine tumors with recombinant Myxoma viruses
… mice bearing intracranial melanoma or lymphoma tumors demonstrated that a single inoculation of intratumoral (IT) MYXV:Tomato was safe but did not produce any significant increase in survival, while studies using intracranial GL261 were inconclusive. However, other studies have shown that MYXV …
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Deciphering the heterogeneity and spatial architecture of tumors
Cancer is caused by the accumulation of somatic mutations that form distinct populations of cells, called clones. The resulting intra-tumor heterogeneity evolves temporally, as well as spatially, and is the main cause of relapse and resistance to treatment. With decreasing costs in DNA sequencing …
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Engineering antibodies for improved targeting of solid tumors
… antigens. Unfortunately, attempts to treat solid tumors with these drugs are often limited by an inability of the antibodies to fully penetrate the tumor tissue, leaving large regions of untargeted and viable cells. The goal of this thesis is to understand the transport phenomena that contribute …
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Thermal Detection of Embedded Tumors using Infrared Imaging
… can prove to be a valuable tool in locating tumors if combined with such an algorithm.
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