Global ETD Search

IMPLEMENTATION OF 3D CELLULAR MODELS FOR DRUG AND TOXIN TESTING IN HEALTHY AND CANCEROUS TISSUE

Forsythe, StevenWake Forest University2018

… we employed bioengineered 3D liv er and cardiac organoids biofabricated from multiple physiologically relevant human cell groups to represent healthy tissue , and tumor organoids derived from colorectal cancer cells from established cell lines to screen multiple materials for toxic effect, …

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Clinical importance of autophagy dependency and inhibition in cancer treatment

Van Eaton, Kristen M., author, Gustafson, Daniel L., advisor, Munsky, Brian, committee member, Thamm, Douglas, committee member, Thorburn, Andrew, committee member, Yao, TingTing, committee memberColorado State University. Libraries2021

… to many chemotherapies. More autophagy dependent tumors are generally more sensitive to autophagy inhibition genetically and pharmacologically. Therefore, determining what tumors are autophagy dependent is important for selecting patients that are viable candidates for autophagy inhibition. …

colostate Repository record for Clinical importance of autophagy dependency and inhibition in cancer treatment (opens in a new tab)

Development of advanced 3D tissue models and O2 imaging methodologies

Jenkins, JamesNational University of Ireland. School of Biochemistry and Cell biology2016

ghent Repository record for Development of advanced 3D tissue models and O2 imaging methodologies (opens in a new tab)