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Showing 1 to 17 of 17 for “"Tumor markers"”.
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Intrinsic Spectroscopic Tumor Markers Revealed by Double-Differential Analysis of Near-Infrared Absorption Spectra
… saturation, fat content, and water content. Tumors display changes in these parameters; however, it is debatable whether they are specific ""signatures"" of cancer. Thus differential diagnosis (benign vs. malignant) solely based on changes in normal tissue components has been difficult. The …
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Automated synthesis of the Lewis blood group oligosaccharides
Cell-surface carbohydrates are markers of specific cell types. These oligosaccharides are involved in recognition, adhesion, and signal transduction events. Advances in molecular glycobiology rely heavily on straightforward access to structurally defined oligosaccharides, but traditional syntheses …
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Αυτοάνοσες εκδηλώσεις και μονοκλωνική εξεργασία στη Β λεμφοκυτταρική νεοπλασία
… that such immunoglobulins could be useful tumor markers. Autoimmune parameters in NHL were not found to be significantly different from these of patients with solid tumors or the normal controls. For this study, a polyclonal antiidiotype was prepared against a monoclonal IgMk rheumatoid …
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Correlation of Caveolin-1 Expression on Tissue Microarray with Prognosis in Renal Cell Carcinoma
… been utilized for rapid profiling of molecular tumor markers and compares well to results obtained by standard methods. Caveolin-1 is a major structural component of caveolae, which are plasma membrane microdomains implicated in the regulation of intracellular signaling pathways. Altered …
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Technologies for the isolation of circulating tumor cells
Metastasis, the spread and growth of tumor cells from the primary site to distant organs, is arguably the most devastating and deadly attribute of cancer, and is ultimately responsible for 90% of cancer-related deaths. Circulating tumor cells (CTCs) are exceedingly rare cells found in the whole …
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Targeting Nanoparticles to Tumor Vasculature
Targeting tumor vessels represents an indirect therapeutic approach in oncology by shifting the treatment away from the tumor cells themselves. Endothelial cells are generally considered genetically stable and do not use escape mechanisms against chemotherapeutic agents as frequently as tumor cells …
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Bead-basierte Fluoreszenz-Immunoassays zum Nachweis tumorinduzierter Proteine
… due to diagnosis via optical methods by which a tumor cannot be found till 300 to 400 days after incidence. In contrast, autoantibodies against tumorsuppressor p53 can be detected in blood serum 100 days after tumor development. As a diagnosis in this early stage is supposed to result in …
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CLINICAL VALIDATION OF 371 MICRO-RNA USE IN SMALL TESTICULAR MASSES AND IN STAGE IIA AND IIB<3CM TESTICULAR GERM CELL TUMORS
… sensitivity and specificity exceed the available markers. We tested its diagnostic accuracy in small testicular masses and in low volume retroperitoneal disease (Stage IIA or IIB). In the first setting we know that up to 70% of small testicular lesions (<20 mm) are benign. Conversely, in the …
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Discovery and Development of Predictive Biomarkers for the Personalization of Pemetrexed Therapy in Non-Small Cell Lung Cancer
… To elucidate mechanisms of response, intratumoral mRNA levels of TYMS and pemetrexed-related genes did not have any significant correlation with response. However, microarray expression profiling, RNA-Seq and western blot analysis independently highlighted FTCD overexpression can be found …
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A new prompt gamma spectroscopy-based approach for range verification in proton therapy
… translates into a high dose conformality in the tumor, as well as into a superior sparing of normal tissue compared to conventional radiotherapy with photons. Today, there are 107 proton therapy and 14 carbon ion centers operating worldwide, and many new ones are under construction. In Italy, the …
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ΔΙΕΡΕΥΝΗΣΗ ΤΟΥ ΡΟΛΟΥ ΤΟΥ ΕΙΔΙΚΟΥ ΠΡΟΣΤΑΤΙΚΟΥ ΑΝΤΙΓΟΝΟΥ (PSA) ΣΤΗΝ ΠΑΘΟΛΟΓΙΑ ΤΟΥ ΠΡΟΣΤΑΤΗ
… FOLLOWING TOTAL PROSTATECTOMY OWING TO RECURRENT TUMOR WITH METASTASES. PSA MIGHT BE AS THEMARKER OF CHOICE TO MONITOR THERAPY FOR PROSTATIC CARCINOMA.
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ΜΕΛΕΤΗ ΤΩΝ ΡΙΒΟΝΟΥΚΛΕΑΣΩΝ ΤΟΥ ΟΡΟΥ ΤΟΥ ΑΙΜΑΤΟΣ ΣΕ ΥΓΙΕΙΣ ΚΑΙ ΑΣΘΕΝΕΙΣ ΜΕ ΚΑΡΚΙΝΟ ΚΑΙ ΜΙΑΣ ΠΡΩΤΕΙΝΗΣ ΠΟΥ ΠΑΡΕΜΒΑΙΝΕΙ ΣΤΗ ΔΡΑΣΗ ΤΟΥΣ
FIVE RIBONUCLEASES WERE PURIFIED FROM THE SERUM OF NORMAL HUMAN SUBJECTS. THE PROPERTIES OF FOUR OF THEM WERE IDENTICAL TO THOSE OF THE SECRETORY TYPE RIBONUCLEASES (OPTIMUM PH 8 AND FASTER HYDROLYSIS OF POLY-C COMPARED TO POLY-K). THE FIFTH ENZYME, WITH THE LOWER MOL. SIZE, HYDROLYZED FASTER …
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Ο ΒΑΘΜΟΣ ΓΛΥΚΙΩΣΗΣ ΤΗΣ Α1-ΟΞΙΝΗΣ ΓΛΥΚΟΠΡΩΤΕΙΝΗΣ ΤΟΥ ΟΡΡΟΥ ΩΣ ΔΕΙΚΤΗΣ ΣΕ ΚΑΚΟΗΘΗΝΕΟΠΛΑΣΙΑ
ΣΤΗΝ ΠΑΡΟΥΣΑ ΔΙΑΤΡΙΒΗ ΜΕΛΕΤΗΘΗΚΕ Ο ΒΑΘΜΟΣ ΓΛΥΚΙΩΣΗΣ ΤΟΥ ΜΟΡΙΟΥ ΤΗΣ Α1- ΟΞΙΝΗΣ ΓΛΥΚΟΠΡΩΤΕΙΝΗΣ (Α1AGP) ΜΕ ΤΗΝ ΜΕΘΟΔΟ ΤΗΣ ΑΝΟΣΟΗΛΕΚΤΡΟΦΟΡΗΣΗΣ ΣΥΓΓΕΝΕΙΑΣ ΔΥΟ ΔΙΑΣΤΑΣΕΩΝ ΜΕ CONCANAVALIN A ΣΤΗΝ ΠΡΩΤΗ ΔΙΑΣΤΑΣΗ. ΜΕΛΕΤΗΘΗΚΕ ΤΟ ΑΝΟΣΟΗΛΕΚΤΡΟΦΟΡΗΤΙΚΟ ΠΡΟΤΥΠΟ ΤΗΣ Α1AGP (PATTERN) ΣΕ ΑΣΘΕΝΕΙΣ ΜΕ ΝΕΟΠΛΑΣΜΑΤΑ …