Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Tumor Infiltrating Immune Cells"”.
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Single-cell analyses of tumor-infiltrating immune cells
… a key problem due to the limited numbers of cells involved, and current methodologies that do not lend themselves well to the discovery of novel cell subpopulations. In this thesis, we investigate the use of various immunophenotypic and transcriptomic single-cell assays to characterize …
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Host-intrinsic factors determine anti-tumor efficacy of exercise in pancreatic ductal adenocarcinoma
… Exercise induces a variety of changes in the tumor microenvironment with beneficial effects in several tumor types. However, our understanding of the clinical effects of exercise and the mechanisms that mediate anti-tumor effects are limited in pancreatic cancer.</p> <p>In this project, using …
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Simultaneous Induction of Nkg2D and Nkg2D Ligand For Promoting Immune Surveillance By Il-12 Plus Doxorubicin Treatment
… 2, member D) and its ligands interaction in tumor microenvironment directs tumor infiltrating immune cells to recognize tumor cells, stimulate cytotoxic effector immune cells, and therefore eradicate tumor cells. IL-12, a cytokine produced by antigen presenting cells, has remarkable antitumor …
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Identification and Knockout of Immunodominant Endogenous Retroviral Antigen in Murine Tumor Models
… have demonstrated the dominant role of T cells in an anti-tumor response, but the functional role of B cells and their antibodies in cancer remains less clear. In murine tumor models, curative immunotherapies have been previously shown to result in the development of immunotherapy-induced …