Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Tumor Dormancy"”.
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Identifying Epigenetic Regulators Of Tumor Dormancy And Recurrence
… largely due tometastatic recurrence. Recurrent tumors arise from residual tumor cells, which can survive cancer therapy and stay dormant for an extended period of time. Despite their clinical importance, the biology of tumor dormancy and recurrence are poorly understood. Using a HER2 inducible …
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Inflammation triggers Zeb1-dependent escape from tumor dormancy
… occurs many years after treatment of the primary tumor. Inflammation, through the orchestra of immune cells and released inflammatory cytokines, can predispose certain tissues to cancer development and can create a favorable environment for metastatic outgrowth. I evaluated whether …
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A Theoretical Model Of Breast Tumor Metastases In The Context Of Tumor Dormancy
… considered as a late event in the primary tumor process. Recent evidence suggests that tumor cells dissemination may occur when the tumor is at a size that does not normally warrant a systemic treatment. Current breast cancer models developed as part of the Cancer Intervention and …
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Examining the Role of Regulatory Lymphocytes in a Mouse Model of BCL1 Tumor Dormancy
Cancer dormancy is a clinical state where residual tumor cells persist for long periods but do not cause detectable disease. However, tumor regrowth can occur and is accompanied by resistance to treatment and high mortality rates. The mechanisms that mediate tumor dormancy have been studied using …
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The Role of The Diras Family Members In Regulating Ras Function, Cancer Growth and Autophagy
<p><em>DIRAS3 </em>is a maternally imprinted tumor suppressor gene that is downregulated by multiple mechanisms across several tumor types. When re-expressed, DIRAS3 decreases proliferation, inhibits motility, and induces autophagy and tumor dormancy. <em>DIRAS3</em> encodes a 26 kDa small GTPase …
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Nuclear receptor TLX and dietary habits: Identifying new targets for the treatment and prevention of metastatic breast cancer
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01