Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Tuft Cells"”.
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Sensory Neurons Initiate Tuft Cell-Dependent Sinonasal Allergic Inflammation via Substance P
The precise role and potential interactions of tuft cells with trigeminal sinonasal neurons in the context of allergic disease remain largely unexplored and unclear. This study investigated the impact of intranasal administration of house dust mite or fungal allergens on these cells and sought to …
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Identify the regulatory roles of intestinal secretory cell lineages during gut inflammation
… the roles of secretory intestinal epithelial cells, specifically tuft cells and enteroendocrine cells (EECs), in colonic inflammation, revealing novel cellular and molecular dynamics. The initial study utilized IEC-specific Hnrnp I knockout mice to demonstrate significant upregulation of …
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Exploring INSL5 and RXFP4 in the gut-brain axis and their potential role in feeding behaviour
… chemogenetic manipulation of Rxfp4-expressing cells influence feeding behaviour in mice. As feeding is regulated, in part, by neuroendocrine signalling in the gut-brain axis (GBA), we aimed to examine INSL5/RXFP4 activity at each level of the GBA to determine the potential mechanisms by which …
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Human intestinal cells across space and time
Cells of the human intestinal tract undergo dynamic changes from development to adulthood and in response to environmental stimuli. Recent advances in high-throughput profiling of cells using transcriptomic approaches have vastly expanded the catalogue of cells that are found across the human body. …