Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 10 of 10 for “"Tuberculosis infections"”.
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Detection of mixed Mycobacterium tuberculosis infections in South African TB Patients
… that TB disease resulted from one infecting M. tuberculosis strain leading to heightened immune protection against subsequent infections, has been revised. Epidemiological studies and the advances in molecular genotyping techniques have highlighted the rapidly frequent isolation of several …
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The development and evaluation of a polymerase chain reaction assay for the diagnosis of mycobacterium tuberculosis infections
The diagnosis of Mycobacterium tuberculosis by conventional techniques is associated with a number of problems which include lack of sensitivity (microscopy) and prolonged incubation periods (laboratory culture) . For these reasons various "rapid detection" methods have been developed but none of …
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The role of Cysteinyl leukotriene type 1 receptor (CysLTR1) during Listeria monocytogenes and mycobacterium tuberculosis infections in mice
… responses, its function during bacterial infections remains unclear. Our study aims to elucidate the role of CysLTR1 in disease progression using C57BL/6 and Balb/c mice infected either with Listeria monocytogenes (Lm) or with Mycobacterium tuberculosis (Mtb). Using CysLTR1 knockout …
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Perceptions of youth regarding the consequences of unsafe lifestyles regarding transmission of HIV and TB in Meadowlands, Gauteng Province
Human Immunodeficiency Virus and Tuberculosis are the most investigated and analysed topics worldwide. However, there is a knowledge gap among the youth concerning the consequences of unsafe lifestyle on the transmission of Human Immunodeficiency Virus and Tuberculosis coinfection. The aim of this …
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Tuberculosis In paediatric kidney transplant recipients a single centre experience
Background: Tuberculosis remains a major challenge in transplantation particularly in endemic countries. The incidence, clinical manifestations, and optimal investigations for TB specifically in the paediatric post-transplant population have not yet been adequately studied. This study aims to …
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Development of a risk score for constrictive pericarditis using the Investigation of the Management of Pericarditis randomised clinical trial dataset
Despite the recent global decline of tuberculosis infections, constrictive pericarditis, one of the most serious consequences of tuberculous pericarditis, continues to be a major cause of morbidity and mortality in sub-Saharan Africa. Currently, while the risk of constrictive pericarditis in …
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Bioinformatic identification and characterization of cytokinetic regulators in Mtb
… of understanding of Mtb regulation during latent tuberculosis infections (LTBI), which comprises the vast majority of tuberculosis cases, has hindered global eradication efforts. To elucidate mechanisms associated with transition to the non-replicating persistent (NRP) state associated with LTBI, …
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The Northern Powerhouse. A multidisciplinary study of the mortality and morbidity of Northern English communities in the 19th century
… evident through the analysis of data regarding tuberculosis infections. It revealed that our understanding of the percentage of infected individuals who present with bone lesions is quite accurate within 19th century sites when compared with the mortality data of the GRO. The impact of …
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The mechanistic basis of susceptibility and resistance to the antitubercular drug para-aminosalicylic acid
Tuberculosis (TB) is responsible for the deaths of 1.6 million people worldwide each year and is the leading cause of death by the pathogen Mycobacterium tuberculosis. The treatment regimen for M. tuberculosis involves lengthy, intensive drug therapy that causes severe side-effects. The …
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Transmission of tuberculosis in high school students in Worcester, South Africa
… have the highest force of Mycobacterium tuberculosis infection1 and rapidly increasing burden of tuberculosis (TB) disease through 10–19 years of age,2 there are few studies on adolescent Mycobacterium tuberculosis infection, transmission, and TB disease in the WHO African region. …