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Showing 1 to 3 of 3 for “"Tsa1"”.
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The Thiol Specific Antioxidant (TSA1) Gene is Required for Survival in Macrophages and Oxidative Stress Resistance in Histoplasma Capsulatum
… <p>The thiol specific antioxidant gene, <em>Tsa1,</em>is strongly upregulated in the yeast (pathogenic) morphotype. This data led to the hypothesis that this gene plays a role in protecting <em>Hc</em>from host mediated oxidative attack. To characterize <em>Tsa1 </em>function, a knockdown …
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Thiol-Based Misfolding: Linking Redox Balance to Cytosolic Proteostasis
… and recruits chaperones such as Hsp104 and Tsa1. These chaperones assist in clearing existing aggregates and preventing further damage. Above all, protein aggregation as a result of exposure to thiol-specific stress extends to human cells, thus establishing a conserved mechanism and model …
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The effects of elevated mitochondrial hydrogen peroxide in S. cerevisiae : a physiological role for cytochrome c peroxidase
… strain deficient in thioredoxin peroxidase (x tsa1 ), and its possible involvement in redox signaling, is also discussed.