Global ETD Search
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Showing 1 to 20 of 208 for “"Trypanosoma"”.
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Regulation of Intracellular pH and Plasma Membrane Potential in Trypanosoma Cruzi and Trypanosoma Brucei
Regulation of intracellular pH (pHi) and the plasma membrane potential (DeltaPsi) was investigate in all stages of the pathogenic protozoans, T. cruzi and T. brucei utilizing the pH sensitive fluorescent dye BCECF and the potentiometric fluorescent dye bisoxonol. pH i in T. cruzi was found to be …
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Cytochemical studies on Trypanosoma ranarum
… in studies on cytoplasmic inclusions in Trypanosoma diemyctli, a parasite of the American newt Diemyctylus viridescens. He noted, particularly, the rapid appearance of well-defined “primary” granules in the region of the kinetoplast and the more gradual appearance of “secondary,” or …
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Histone Modifications in Trypanosoma Brucei
<p>Trypanosoma brucei maintains an infection in its mammalian host by switching its surface antigen, thus evading host antibodies, in a process known as antigenic variation. Variant surface glycoproteins (VSG), the surface antigen, are expressed from genes located at as many as 20 Expression Sites …
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UTR prediction programs for trypanosoma brucei
In the past few years, the field of bioinformatics has seen a rapid increase in the need for use of various sequence analysis tools. As we advance in the fields of science and technology, new programs and software are constantly being developed in this field. Rapidly expanding gene sequence …
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The PUF proteins in Trypanosoma brucei
The protozoan parasite Trypanosoma brucei, which causes human sleeping sickness, has to adapt to rather different environments as it cycles between the mammalian host and the tsetse fly vector. This adaptation is mediated by changes in trypanosome gene expression, which are mainly regulated at the …
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Studies on fucosylation in Trypanosoma brucei
… recently shown to be essential in the parasite Trypanosoma brucei. Fucose is a common sugar modification on eukaryotic glycan structures, but it has not been well described in trypanosomatids. To elucidate the role of fucose in T. brucei we searched for putative fucosyltransferases in this …
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Genómica y transcriptómica comparativa de Trypanosoma Cruzi
El parásito Trypanosoma cruzi es conocido como el agente etiológico de la enfermedad de Chagas, según reportes de la Organización Mundial de la Salud (OMS) se encuentra dentro de las 17 enfermedades tropicales desatendidas y es la tercera infección parasitaria más común en todo el mundo después de …
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Regulation of Gene Expression in Trypanosoma brucei
<p>The protozoan parasite Trypanosoma brucei is one of the most divergent well-studied eukaryotes and many discoveries of general interest have been made in T. brucei. Atypical for a eukaryote, in T. brucei genes transcribed by RNA polymerase II (RNA pol II) are arranged in polycistronic …
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Immune RNA Activity in Trypanosoma Lewisi Infections
Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs
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Molecular mechanism of Trypanosoma brucei Aquaglyceroporin 2
Trypanosoma brucei subspecies cause Human African Trypanosomiasis, which is fatal unless treated. T. brucei Aquaglyceroporin 2 (TbAQP2) is required for the uptake of two of the drugs used clinically, pentamidine and melarsoprol. TbAQP2 mutations or the formation of a chimeric gene with TbAQP3 …
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Essentiality and Regulation of Deoxyhypusination in Trypanosoma brucei
… trypanosomiasis is caused by protozoan parasite Trypanosoma brucei. T. brucei and other trypanosomatids require spermidine for the formation of trypanothione, a unique thiol-redox factor. In other eukaryotes, spermidine is essential for the (deoxy)hypusination of eukaryotic initiation factor 5A …
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Biological studies of GPI-anchoring in Trypanosoma cruzi
Trypanosoma cruzi, a protozoan parasite transmitted to humans via triatomine\r\ninsects, causes chronic chagasic cardiomyopathy (CCM) in ~30% of infected individuals.\r\nThis dissertation sought to characterize T. cruzi’s pathogenic mechanisms by cellular,\r\nbiochemical, and molecular genetics …
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Nutritional, environmental and morphological studies on Trypanosoma ranarum
The in vitro cultivation of Trypanosome ranarum has been accomplished in complex nutrient solutions, but growth in chemically defined media has never been attempted. The purpose of the study was to cultivate R. ranarum in “purified” bacterial media ingredients and to determine the basic nutrient …
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Antigenic Variation and Telomere Structure in Trypanosoma brucei
<p>Trypanosoma brucei survives immune attack in its mammalian hosts by periodically changing the variant surface glycoprotein (VSG). From the ~1000 VSG genes (VSGs) scattered throughout the genome, a few are located at telomere loci called expression sites (ESs) and only one is expressed at any …
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Investigation of conserved Flagellum proteins in Trypanosoma brucei
The single celled protozoan parasite Trypanosoma brucei is an excellent model organism to study eukaryotic cilia and flagella as it has a single flagellum that remains assembled throughout the cell cycle. The new flagellum assembles in a known position relative to the old flagellum, therefore …
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Linkage mapping and genetic analysis of Trypanosoma brucei
Trypanosoma brucei is a protozoan parasite of major public health and economic importance in sub-Saharan Africa, where it is the causative agent of sleeping sickness in man and Nagana in cattle. The complete genome sequence of T.brucei is now available and the diploid genetic system has recently …
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Biological Studies on Various Strains of Trypanosoma Avium
The purpose of this study was to further investigate avian trypanosomids, relative to the Magpie, Steller's Jay, and Sparrowhawk, and to initiate work for a newer aspect of trypanosome study; the effects of radiation upon trypanosome growth in vitro.
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