Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Tropoelastin"”.
-
Molecular structure, hierarchical assembly and stimuli-responsive mechanics of tropoelastin and elastin biomaterials
… polymer, assembled from its molecular precursor tropoelastin, is the dominant component of elastic fibers, which confer elasticity and structural integrity to skin, lung, connective and vascular tissue. Historically, elastin's dynamic nature has precluded traditional approaches such as X-ray …
-
Characterization and Modulation of the Emergent Material Properties of Biomolecular Condensates
… we next examined a model system based on tropoelastin, an extracellular protein relevant in connective tissue assemblies like lungs, arteries, and cartilage. The coacervation and cross-linking process of tropoelastin culminates in the formation of elastin fibers, a resilient biomaterial …
-
Involvement of TGF-beta in skin photoaging
… produced by TGF-[beta] are key components in the tropoelastin (TE, a soluble precursor of elastin) up-regulation in dermal fibroblasts, and that TGF-[beta] is a major regulator in the photoaging processes. Using human skin fibroblasts system in vitro, we found that ROS generated from NADPH oxidase …
-
The Effect of Fascicular Elastin on the Mechanical and Functional Properties of Healthy, Damaged, and Healing Tendon
… partial AT transection and treatment injections (tropoelastin, saline, or no injections). Notably, we found non-injected Prx1Cre+;Elnfl/fl mice exhibited worse functional (i.e., gait) outcomes than all other groups, as measured by high-speed video and a custom automated DeepLabCut/Python pipeline. …
-
Strategies to design and optimize natural polymers as biomaterial inks for musculoskeletal tissue engineering applications
… the addition of different bioactive cues (i.e. tropoelastin or bioceramics) providing a versatile platform for the development of biomaterial inks for bone regeneration.
-
Photorejuvenation Induced by 5-Aminolevulinic Acid Photodynamic Therapy in the Patients with Actinic Keratosis: A Histological Analysis
… material with co-localizing fibrilline-1 and tropoelastin expression in the dermis tended to decrease after treatment. The expression of matrix metalloproteinases -1, -3, and -12 was also decreased. Conclusion: The histological evidence showed beneficial effects of ALA-PDT for photodamaged …
-
Syntax of Phase Transition Peptide Polymers with LCST and UCST Behavior
<p>"Smart" polymers that sense stimuli in aqueous environments and that respond with a pronounced change in their solvation are of great utility in biotechnology and medicine. Currently, however, only few peptide polymers are known to display this behavior. Here, we uncover the syntax -- defined as …
-
Characterisation of novel matrix-binding interactions for latent transforming growth factor-β-binding protein-2 (LTBP-2), with emphasis on heparin and heparan sulphate proteoglycans.
… and through this interaction it may target tropoelastin-fibulin-5 complexes on to fibrillin-1-microfibrils during elastic fibre assembly. In order to understand more about the role of LTBP-2 in the assembly of elastic fibres and to identify other novel functions, this study involved …