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Showing 1 to 8 of 8 for “"Trna Splicing"”.

  1. Structure and Function Studies on tRNA Splicing Endonuclease

    Underwood, Justin G, <p>0009-0008-5795-0150</p>2025

    <p>A subset of eukaryotic pre-tRNAs have introns that must be spliced out to become mature molecules capable of functioning in translation. This essential processing step is performed by tRNA splicing endonuclease (TSEN), a highly conserved heterotetramer with two catalytic and two structural …

    uthsc Repository record

  2. Functions of The Trna Splicing Endonuclease and Other Adventures In Rna Processing

    Hurtig, Jennifer, van Hoof, Ambro, <p>0000-0003-1243-1492</p>2024

    <p>The tRNA splicing endonuclease (TSEN), has been studied for over three decades for its function in tRNA splicing. However, this enzyme has other functions that are just beginning to be characterized. Mutations in TSEN cause the neuronal disease pontocerebellar hypoplasia (PCH) that is …

    uthsc Repository record

  3. Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases

    Ahammed, Khondakar Sayef, <p>0000-0001-9403-0937</p>2026

    <p>Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases</p> <p>Khondakar Sayef Ahammed, M.S.</p> <p>Advisory Professor: Ambro van Hoof, Ph.D.</p> <p><strong> </strong></p> <p>RNA maturation and degradation reactions are important for health and survival of all …

    uthsc Repository record

  4. The Phosphatase Activities of T4 Polynucleotide Kinase (Rna Ligase, Splicing)

    Weber, Thomas RichardUniversity of Illinois at Urbana-Champaign2014

    … the 2':3'-cyclic phosphate in the mechanism of tRNA splicing in wheat germ and yeast prompted a closer examination of the 3'-phosphatase activity of T4 polynucleotide kinase. This resulted in the discovery of not only a 2':3'-cyclic phosphatase activity but also a 2'-phosphatase, in addition to …

    uiuc Repository record

  5. Characterization of RNA damage and repair in bacteria

    Raybarman, AdrikaUniversity of Illinois at Urbana-Champaign2024

    Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01

    uiuc Repository record

  6. Biochemical and structural studies of RNA damage and repair in bacteria

    Carruthers, Amy LynnUniversity of Illinois at Urbana-Champaign2019

    … that are necessary for translation mainly, tRNAs and rRNAs which can result in their loss of function. In order to respond to RNA damage, some organisms have developed RNA repair systems which can heal and seal the cleaved RNA molecule to restore its function. For example, two proteins in …

    uiuc Repository record

  7. Mechanismus des pre-tRNA-Spleißens : Struktur und Funktion pflanzlicher und animaler RNA-Ligasen

    Englert, MarkusUniversität Würzburg

    … werden von der RNA Polymerase III als Vorläufer tRNA transkribiert und durchlaufen eine Vielzahl von Reifungsschritten hin zur maturen tRNA. Neben der Hydrolyse der 5´- und 3´-Flanke durch die RNase P und die tRNase Z, sowie einer Vielzahl von Basenmodifizierungen, wird bei einigen pre-tRNAs das …

    wurz-thes Repository record

  8. CP1 domain of leucyl-tRNA synthetase: dissecting its dual roles in amino acid editing and RNA splicing

    Sarkar, JayaUniversity of Illinois at Urbana-Champaign2012

    Item marked as restricted to the 'Administrator' Group (id=1) by William Ingram (wingram2@illinois.edu) on 2012-06-27T21:32:36Z Item is restricted until 2014-06-27T21:32:23Z

    uiuc Repository record