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Showing 1 to 3 of 3 for “"Triplehelix"”.

  1. Kupplung der DNA-Methyltransferase M.SssI mit Triplehelix-bildenden Oligodesoxynucleotiden

    Monami, Amélie JoséphinePublikationsserver der RWTH Aachen University2007

    DNA modifying enzymes, like DNA methyltransferases (DNA MTases) and restriction endonucleases (REases), could in principle be used to map or manipulate genomes. However, these enzymes are inappropriate for that purpose because of their generally short recognition sequences. An increase of their …

    aachen Repository record

  2. Hemmung der ICAM-1-Genexpression durch Triplehelix-Oligonukleotide™

    Besch, RobertLudwig-Maximilians-Universität

    lmu-germany Repository record

  3. Biophysikalische Charakterisierung und biochemische Steuerung von Methyltransferase-DNA-Wechselwirkungen

    Bahr, MatthiasPublikationsserver der RWTH Aachen University2009

    … of an MTase which is covalently linked to a triplehelix-forming oligonucleotide (TFO) were investigated. This conjugate has been synthesised in previous works and exhibits dramatically increased sequence specificity compared to the unmodified MTase. A very sensitive and straightforward …

    aachen Repository record