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Showing 1 to 20 of 64 for “"Trimethoprim"”.
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Characterisation of trimethoprim resistance transposons and their gene products
… P-20, isolated from pigs, was shown to owe its trimethoprim resistance to two different plasmid/transposon mediated resistance genes. One gene, mobilised by RP4, was located on a 4 - 6 kb transposon designated Tn4135, and resulted in the mediation of transferable high level trimethoprim …
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Trimethoprim-Based Chemical Tags for High Resolution Live Cell Imaging
… photon-output and tailored functionalities. The trimethoprim-based chemical tag (TMP-tag) was initially developed based on the high affinity interaction between E.coli dihydrofolatereductase and the antibiotic trimethoprim and subsequently rendered covalent and fluorogenic via proximity-induced …
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Removals of sulfonamide and trimethoprim antibiotics in municipal wastewater by biological treatment processes
… and the commonly co-applied antibiotic trimethoprim, in aqueous and solid phases of wastewater. The complex wastewater matrices were shown to result in significant and unpredictable signal suppression for the analysis. Correction of such matrix effects was essential in order to achieve …
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A retrospective study to evaluate the efficacy of trimethoprim/sulfamethoxazole (TMP/SMX) compared to daptomycin or linezolid for the treatment of infections due to methicillin-resistant <i>staphylococcus aureus</i> (MRSA)
… and Linezolid, two new, expensive drugs, and trimethoprim/sulfamethoxazole(TMP/SMX), an old, inexpensive agent. Study aims were to compare the clinical efficacy and potential cost savings associated with TMP/SMX use.</p> <p>Methods: A retrospective study was conducted at Detroit Medical …
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Investigation of ciprofloxacin antibacterial combinations.
… determine whether combining ciprofloxacin with trimethoprim and or a sulphonamide could prove clinically beneficial. The microbiological activity of the antibacterials used either alone or in combination was studied using in vitro techniques, against cultures of P. aeruginosa, S. aureus and …
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Incidence of bacteraemia in HIV-infected children in Africa, and the impact of highly active antiretroviral therapy
… In addition, they were randomized to receive trimethoprim/sulfamethoxaxole prophylaxis on either a daily or a three-times-per-week schedule. The aim: To describe the incidence of bacteraemia, and the spectrum of organisms cultured. To determine if there was a difference in the incidence of …
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PHOTOELECTROCATALYTIC OXIDATION OF MUNICIPAL REVERSE OSMOSIS CONCENTRATE
… system was first applied to the degradation of trimethoprim. The effects of essential operational parameters were studied, with the focus on chloride. The results reveal that reactive chlorine species (RCS) converted from chloride could greatly affect the degradation efficiency as well as the …
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The synthesis and biological evaluation of a library of autoinducer-antibiotic conjugates
… its group behaviours. Ciprofloxacin and trimethoprim were chosen as the antibiotic partners. Ciprofloxacin is commonly used against \textit{P. aeruginosa} but resistance to it is developing, whereas \textit{P. aeruginosa} is inherently resistant to trimethoprim. It was hypothesised that …
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REMOVAL OF EMERGING CONTAMINANTS FROM AQUEOUS SOLUTION BY OZONE -BASED PROCESSES
… and three pharmaceuticals sulfamethoxazole, trimethoprim and carbamazepine have been selected. The effect of different process parameters such as chemical dosages, ozone weight percent, ozone flow rates, etc. on destruction of ECs were examined. It was observed that 1, 4-dioxane were …
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Requirements and strategies for winning the battle against antibiotic resistance by antisense technology
… block progression of antibiotic resistance for trimethoprim. Converge bacteria to desired mutations. Using antisense molecules to induce loss of trimethoprim resistance mutations
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Implementing formulary recommendations in primary care: effect on patient outcomes.
… 12 randomly selected high and low prescribers of trimethoprim, the recommended agent, each agreed to distribute 20 patient questionnaires. Following a period of 18 months and despite repeated contact with the GPs, only 89/480 (19%) questionnaires had been distributed. Patient response was, …
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Pharmaceuticals removal in soil following wastewater land application
… limits for all samples while carbamazepine and trimethoprim were detected in every soil and plant sample. Carbamazepine was detected at higher concentrations in the soil and plant samples comparing to trimethoprim while the calculated plant bioconcentration factor for trimethoprim was higher …
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Molecular identification and antibiogram profiling of Avibacterium Paragallinarum and co-pathogenic bacteria assiciated with respiratory infections in chickens at Groot Aub settlement, Khomas region
… but resistant to gentamycin, ciprofloxacin and trimethoprim sulfamethoxazole. On the contrary, all isolated co-pathogenic bacteria were resistant to tetracycline and sensitive to trimethoprim sulfamethoxazole, ampicillin and ciprofloxacin. These results indicate that Avibacterium paragallinarum …
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Antimicrobial resistance patterns of foodborne bacterial isolates from HIV/AIDS patients in Lusaka, Zambia.
… resistant to ampicillin and sulfamethoxazole/trimethoprim with 95.4% and 80.95% resistance respectively. Foodborne bacteria such as Staphylococcus aurues isolates were 100% resistant to azithromycin and 90.90% resistant to methicillin. While Salmonella paratyphi isolate was 100% resistant to …
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Antimicrobial resistance patterns of foodborne bacterial isolates from HIV/AIDS patients in Lusaka, Zambia.
… resistant to ampicillin and sulfamethoxazole/trimethoprim with 95.4% and 80.95% resistance respectively. Foodborne bacteria such as Staphylococcus aurues isolates were 100% resistant to azithromycin and 90.90% resistant to methicillin. While Salmonella paratyphi isolate was 100% resistant to …
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Screening and Characterization of Antimicrobial Compounds and Material against Vibrio cholerae
… MMV675968 was identified to function similar to trimethoprim, targeting the dihydrofolate reductase of V. cholerae. This compound has the potential to be developed as a trimethoprim replacement with a minimum inhibitory concentration lower by 14-fold. Next, the antibacterial property of a newly …
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The effects of low-level pharmaceuticals on stream biofilm structure and function across a land-use gradient in streams of the Huron River watershed
… triclosan, diphenhydramine, and sulfamethoxazole-trimethoprim treatments. We found evidence that low levels of these PPCPs affected some, but not all, aspects of biofilm processes and bacterial community composition. Bacterial carbon uptake was reduced (p = 0.06) and we found shifts in biofilm …
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The Removal of Pharmaceuticals from Wastewater by Wet-Air Oxidation
… persistent; specifically, these compounds were trimethoprim (TMP, a basic antibiotic) and gemfibrozil (GEM, an acidic lipid regulator). Treatment of synthetic wastewater that contained these drugs was accomplished using wet-air oxidation (WAO). Pre- and post-treatment drug concentrations were …
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Studies on the stability and activity of polymyxin B solutions.
… with polymyxin B. Thiomersal 0.001 %w/v, trimethoprim 0.02 %w/v and thiomersal 0.001 %w/v plus trimethoprim 0.02 %w/v did not have an effect on the activity of polymyxin B 2000 U/ml. Neomycin was an exception and at the concentrations in the range 0.0192 to 0.16 %w/v exhibited an …
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Synthesis, characterisation and in vitro studies of metal complexes of some selected antimalarial drugs
… complexes derived from chloroquine, amodiaquine, trimethoprim, sulfadiazine, tetracycline and pyrimethamine have been synthesised using the following metal ions: Co(II), Cu(II), Zn(II), Mn(II), Ni(II), Pt(II), Pd(II), Co(III), Fe(III), Ru(III) and VO(II). The complexes were characterised by …
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