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Showing 1 to 2 of 2 for “"Trikentrin A"”.
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Benzannulated indoles as drug discovery templates. Efforts towards the total synthesis of a library of therapeutic candidates inspired by Cis-Trikentrin A
The herbindole and trikentrin indole alkaloids are a series of structurally related natural products, characterized by a 6,7-benzannulated indole core – a structural motif rarely observed in nature. Originally isolated from the Trikentrion flabelliforme, and Axinella sp. sponges, these compounds …
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Indole Arynes in organic synthesis : discovery and applications for the total synthesis of complex natural products
… complex targets include such members as the trikentrins, herbindoles, teleocidins, nodulisporic acids, and penitrems to name just a few representative examples. We discovered the first indole arynes, namely the 5,6- and 6,7-indole arynes (aka indolynes), and provided a vastly superior …