Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 109 for “"Tricyclic"”.
-
Personalizing tricyclic antidepressant treatment for major depressive disorder
Contains fulltext : 329120.pdf (Publisher’s version ) (Closed access)
-
Synthesis of Bicyclic and Tricyclic Analogues of Oxazolidinone
… devoted to the design and synthesis of the fused tricyclic piperazine analogues and tricyclic triazole analogues of ANB-22 and ANB-40. </p><p>By employing the aziridine-ring-opening and the Mitsunobu reaction, a series of fused bicyclic and tricyclic oxazolidinone-piperazine derivatives have been …
-
Tricyclic Steiner Triple Systems with 1-Rotational Subsystems.
… <em>STS</em>(<em>v</em>), is said to be <em>tricyclic</em> if it admits an automorphism whose disjoint cyclic decomposition consists of three cycles. In this thesis we give necessary and sufficient conditions for the existence of a tricyclic <em>STS</em>(<em>v</em>) when one of the cycles is …
-
Bridgehead Reactivity in Some Bicyclic and Tricyclic Systems
Made available in DSpace on 2014-12-10T23:01:52Z (GMT). No. of bitstreams: 1 7414549.pdf: 5862675 bytes, checksum: ee96cdc7c114dea1eab63fe68f33a7c1 (MD5) Previous issue date: 1974
-
The Effects of Acetylenic Tricyclic Bis-(Cyano Enone) on Cell Migration
… invasion, and metastasis. The acetylenic tricyclic bis-(cyano enone), TBE-31, has been shown to be a promising chemopreventative compound. However, its effects on cell migration are unknown. This thesis focuses on deciphering the molecular mechanisms TBE-31 utilizes to inhibit cell …
-
Effects of tricyclic antidepressant drugs on deprivation-induced fluid consumption in rats
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
-
The use of low dose tricyclic antidepressants at Heideveld Community Health Centre
… 3. To see if indications for the use of low dose tricyclic antidepressants are being recorded. 4. To identify the indications for the use of low dose tricyclic antidepressant. METHOD: A total of 500 patient folders were reviewed. 50 patient folders, (10 folders each from five medical officers), …
-
Synthesis and kinetic studies of tricyclic phosphates and phosphonates: Effect of phosphorus-oxide stereochemistry on allylic rearrangements
… In this work, kinetic studies are reported on tricyclic phosphates and phosphonates which were prepared from 11 and 12 step syntheses. First order rate constants for solvolysis (k$\sb{\rm s}$) and loss of optical activity (k$\sb\alpha$) were measured for 12a and 12b under solvolytic conditions …
-
Stereoselective Intramolecular Rhodium(I)-Catalyzed [(3+2+2)] Cycloaddition Reactions of Alkylidenecyclopropanes (ACPs) for the Concise Synthesis of Bridged Tricyclic Products
… synthesis of fused bicyclic and tricyclic systems has been explored, the stereoselective assembly of the more challenging bridged tricyclic skeletons—present in bioactive sesquiterpenes—remains underdeveloped. Chapter 1 introduces transition metal-catalyzed higher-order [m+n+o] …
-
Synthesis of Bicyclic Thieno[2,3-d]Pyrimidines, Tricyclic Thieno[2,3-d]Pyrimidines and Thieno[3,2-d]Pyrimidines as Classical and Nonclassical Antifolates
An introduction, background and research progress in the areas of antifolates and antimitotic agents has been reviewed and discussed. Thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFTase) are important folate dependent enzymes that are …
-
Synthesis and Determination of the Absolute Configuration of the Bicyclic Guanidine Core of Batzelladine A and the Development of a Novel [4+2] Inverse Electron Demand Hetero Diels -Alder Cycloaddition and Its Application Toward the Synthesis of the Tricyclic Guanidine Fragment Within Batzelladine A
… cycloaddition amendable for synthesis of the tricyclic guanidine portion. These studies culminated in the first synthesis of the bicyclic guanidine core within batzelladine A, which was demonstrated by accessing in enantiospecific fashion a suitably protected form of the bicyclic core …
-
A modified synthesis, C-functionalization, resolution and racemization kinetics of cross -bridged tetraazamacrocycles
… The synthesis involves the use of a cis-tricyclic bisaminal intermediate for the preparation of tetracyclic bisaminals and the microwave-assisted reductive ring opening of N,N'-dibenzyl bisaminal salts. The cis-tricyclic bisaminal was also used in the preparation of a C-functionalized …
-
Construction of carbocycles via oxonium ylides generation and rearrangement: towards the synthesis of taxol
… sterically hindered eight-membered ring of the tricyclic core system of Taxol. Described herein is the continuation of efforts focused towards the access of fused medium-ring carbocycles by tandem catalytic oxonium ylide generation and rearrangement. The novel method in which intramolecular …
-
Studies of organophosphorus compounds by nuclear magnetic resonance spectroscopy with two frequency dimensions
… of organophosphorus compounds with bicyclic and tricyclic cage structures has been prepared and studied by n.m.r. spectroscopy.
-
Synthesis of Cylindricine C and its Stereoisomers
… in their structural makeup due to the unusual tricyclic pyrrolo[2,1-j]quinoline framework having a cis-fused azadecalin skeleton. Novel approaches to synthesising these complex molecules are useful due to the difficulty in isolating these compounds from natural sources. Acetylenic sulfones have …
-
Synthetic studies towards total synthesis of bielschowskysin
… kallos, possesses a fascinating tricyclic [5-4-9] ring architecture, unprecedented in the realms of natural products. This diterpene exhibits antiplasmodial activity against several drug-resistant strains of the malaria-causing protozoan parasite, Plasmodium falciparum, at IC50 of …
Page 1 of 6