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Showing 1 to 13 of 13 for “"Triamcinolone"”.
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Effects of sodium hyaluronate and triamcinolone acetonide on proteoglycan metabolism in equine articular chondrocytes treated with interleukin-1
… hyaluronate (HA) alone or in combination with triamcinolone acetate (TA) can mitigate chondrocyte proteoglycan catabolism caused by interleukin-1 (IL-1) administration. Chondrocytes were collected from fetlock joints of ten horses euthanized for reasons unrelated to joint disease. Chondrocyte …
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Interações da trancinolona com ciclodextrinas em sistemas multicomponentes
Triamcinolone is a relevant anti-inflammatory costicosteroid drug, used mainly by injectable suspensions due its poor water solubility. The association of triamcinolone with cyclodextrins and co-solvents (triethanolamine TEA and N-methylpirrolidone NMP) was held to solubilize the drug and explain …
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Binding sites in the nuclear envelope for cytoplasmic glucocorticoid receptor complex
Using tritiated triamcinolone acetonide to monitor purification, cytoplasmic triamcinolone acetonide-receptor complex has been purified 3 000 fold from rat liver cytosol. The isolated complex sedimented as a single radioactive peak on a 5 - 20% sucrose gradient. Nuclear envelopes isolated from …
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Effect of Drugs on Rabbit Retina
… and ranibizumab, but not with bevacizumab. Triamcinolone acetonide is a corticosteroid with depot properties, used for intramuscular and intraarticular injections. In Europe, triamcinolone is commercially available only in combination with the preservative benzyl alcohol, and is not approved …
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Bone Marrow Mononuclear Cell for Equine Joint Disease
… to 1 of 3 treatments: saline (negative control), triamcinolone (positive control), or BMNC (treatment group). Horses were subjectively and objectively evaluated for lameness and synovial fluid collected (cytology and cytokine/growth factor quantification) at 0, 7, and 21 days post-injection. Data …
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Clear, Aqueous Topical Nanomicelle Formulation For Diabetic Macula Edema
… macula edema. The hydrophobic drugs include triamcinolone acetonide (TA), fluocinolonce acetonide (FA) and triamcinolone (T1) were encapsulated with a combination of nonionic surfactant hydrogenated castor oil (HCO) and octoxynol-40 (Oc-40). A design of experiment (DOE) with JMP software was …
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Pentablock copolymers based controlled release formulations of small and macromolecules for ophthalmic applications
… copolymers and in vitro release profile of triamcinolone acetonide (selected as model drug) from nanoparticles was also evaluated. Pentablock polymer with proper ratio PDLLA/PCL was amorphous in nature whereas PLLA containing polymer has semicrystalline nature. Release of triamcinolone …
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Diabetic macular oedema: the role of steroids and VEGF
… junctional proteins. Both hydrocortisone and triamcinolone were able to inhibit vascular endothelial growth factor but not lysophosphatidic acid induced permeability suggesting that steroids are able to counteract the effects of certain but all vasoactive compounds. Overall our results …
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Methods for Increasing Sensitivity and Throughput of Solid-State NMR Spectroscopy of Pharmaceutical Solids
… the crystalline and amorphous solid forms. Triamcinolone was selected for quantitation studies using 19F SSNMR.
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Dendrimer Based Nanotherapeutics For Ocular Drug Delivery
… any side effects. </p> <p>Two different drugs Triamcinolone acetonide (TA) and N-Acetyl Cysteine (NAC) conjugated to G4-OH dendrimers showed tailorable sustained release in physiological relevant solutions and were evaluated in-vitro and in-vivo. Dendrimer-TA conjugates enhanced the solubility …
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Analysis of the Metabolism of Dextran-Methylprednisolone Succinate Using
… (CST) in addition to an internal standard (IS), triamcinolone acetonide. Ratios between drug plasma concentration and IS peak area were determined to be linear in the range of 0.1-4 pglml for MP and M P S , and 0.1- 1.0 pg/ml for MPN and CST. Assay intra- and inter-run errors were less than 8%, …
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Colostrum feeding and its effects on serum cortisol, thyroxine, immunoglobulin G and cytosolic glucocorticoid receptors in skeletal muscle in the bovine neonate
… (29+/-9), testosterone (10+/-3), and triamcinolone (41+/-11).
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Βιοαποικοδομήσιμο σύστημα ελεγχόμενης αποδέσμευσης ακετονικής τριαμσινολόνης για διασκληρική χορήγηση : in vitro μελέτη
Η Ακετονική Τριαμσινολόνη είναι ένα συνθετικό γλυκοκορτικοειδές το οποίο έχει ευρέως χρησιμοποιηθεί στη θεραπεία ενός αριθμού φλεγμονωδών και αγγειακών / εξιδρωματικών παθήσεων του οφθαλμού, χορηγούμενη υπό μορφή ένεσης παραβόλβια, υποτενόνια ή ενδοϋαλοειδικά. Δυστυχώς έχει περιορισμένο χρόνο …