Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 563 for “"Traumatic Brain Injury"”.
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Mitochondrial Fission After Traumatic Brain Injury
… is a central feature in the pathophysiology of Traumatic Brain Injury (TBI). Loss of mitochondrial function disrupts normal cellular processes in the brain, as well as impedes the ability for repair and recovery, creating a vicious cycle that perpetuates damage after injury. To maintain …
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Bioengineering Analysis of Traumatic Brain Injury
Traumatic brain injury (TBI) is a serious health concern affecting over a million people in the UK. Brain shift and herniation, which are closely related to severe disability or death, are important signs of abnormally elevated intracranial pressure (ICP) or space-occupying intracranial mass after …
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Contusion Progression in Traumatic Brain Injury
Cerebral contusions that result from brain trauma have the propensity to enlarge over the days following injury, including extension of the haemorrhage core and swelling of the surrounding peri-contusional brain. This secondary injury increases the likelihood of death and severe disabil- ity, and …
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Autoantibody Responses to Traumatic Brain Injury
Traumatic brain injury (TBI) is the leading cause of death and disability in young adults in the developed world. After accounting for known prognostic factors, there remains marked unexplained heterogeneity in outcome between individuals with overtly similar injuries, and furthermore, around one …
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Intracranial Monitoring after Severe Traumatic Brain Injury
Intracranial monitoring after severe traumatic brain injury offers the possibility for early detection and amelioration of physiological insults. In this thesis, I explore cerebral insults due raised intracranial pressure, decreased cerebral perfusion pressure and impaired cerebral pressure …
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Incidence of traumatic brain injury, prevalence of dysphagia, and factors predicting health outcomes following traumatic brain injury in adults
South Africa has a high incidence of injury-related disorders, such as traumatic brain injury (TBI) as a result of motor vehicle accidents and assault. Dysphagia is a common sequela of TBI, which may result in malnutrition or aspiration pneumonia. There is limited epidemiological data available for …
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Traumatic Brain Injury and Its Effect on Students
Over one million people suffer a traumatic brain injury every year, many of whom are students between the ages of 5 and 18. Using a qualitative case study approach, I wanted to discover the specific factors that both impede and help the school re-entry process for students in grades kindergarten …
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Traumatic brain injury : traditional and narrative assessment techniques
Traumatic brain injury (TBI) causes impairment of executive functioning, as well as cognitive and language abilities of various degrees. Standard language tests currently focus on very specific language disorders and can not identify language disorders of TBI subjects with high-level language …
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Binge Alcohol and Recovery After Traumatic Brain Injury
… 275,000 Americans are hospitalized following a traumatic brain injury (TBI) every year, 80,000 of whom develop a long-term disability. The factor that places one at perhaps the greatest risk of suffering a TBI is alcohol intoxication. 30-50% of TBI sufferers have a blood alcohol level above .08 …
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Longitudinal Behavioral Assessment of Neonatal Traumatic Brain Injury
Traumatic brain injury (TBI) in children and infants is a primary cause of cognitive and behavioral problems that can persist through adulthood. In this study, the long-term behavioral effects of neonatal and juvenile TBI (jTBI) were characterized using mice. At an age of post-natal 7 or 10 days, …
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The Intersection of Traumatic Brain Injury and Homelessness
<p>The rates of TBI are significantly higher among individuals experiencing homelessness compared to the general population. Up to half of individuals experiencing homelessness may have a TBI. Accurate prevalence rates of TBI among individuals experiencing homelessness are difficult to obtain due …
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Mechanisms of Cerebral Autoregulation in Traumatic Brain Injury
… understanding of this detrimental secondary injury process in traumatic brain injury (TBI), there are still unknowns before we can target autoregulatory disturbance in the neurocritical care unit. This thesis addresses two aspects of these unknowns: 1) CA in the previously uncharacterised …
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Decompressive craniectomy in children with traumatic brain injury
Although the conventional role of the operation was that of a salvage procedure when medical therapy failed in the treatment of raised intracranial pressure (ICP), two important concepts have emerged in the recent literature that appear to challenge that approach. In addition to the lack of …
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Computational modeling of blast-induced traumatic brain injury
… effects of blasts on the human head; no injury thresholds have been established for blast effects on the head, and even direct transmission of the shock wave to the intracranial cavity is disputed. Still less is known about how personal protective equipment such as the Advanced Combat …
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Metabolic Changes in Astrocytes Following Traumatic Brain Injury
Traumatic brain injury (TBI) is a globally prominent form of neurological disorder, with millions of people sustaining TBI annually [1]. TBI is known to lead to both short- and long-term neurological effects, many of which occur due to functional changes in the brain after injury [2], [3]. …
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Pragmatic communication following traumatic brain injury in early childhood
Traumatic brain injury (TBI) is one of the most common causes of acquired disability during childhood. Most of the literature to date has used standardized tests to explore the impact of TBI on children's cognitive skills, with little exploration of children's higher level functional skills, …
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Cognitive Mechanisms of Memory Impairment Following Traumatic Brain Injury
Memory impairment is common following traumatic brain injury (TBI). In recent years, researchers have demonstrated that the processes underlying memory formation (working memory, encoding, consolidation, and retrieval) are interrelated but dissociable events.The following study was designed to …
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Rate alterable traumatic brain injury device for rodent models
Traumatic Brain Injury (TBI) is a physical impact to the head resulting in functional deficits in memory and motor systems. TBI is a prevalent problem occurring in 1.7 million people annually in the United States (Faul et al. 2010). TBIs can differ greatly in terms of the biomechanics of the impact …
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Diagnosis Threat in a Mild Traumatic Brain Injury Population
… to participate based on their history of head injury and that they might expect to perform more poorly on testing. Participants in the Control group were told to perform to the best of their ability. It was hypothesized that individuals who had a history of mild Traumatic Brain Injury (mTBI) …
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