Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Transposon-insertion sequencing"”.
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High-throughput experimental and computational studies of bacterial evolution
… technology for probing gene function, transposon-insertion sequencing, and its application to the study of functional differences between two important human pathogens, Salmonella enterica subspecies enterica serovars Typhi and Typhimurium. In a first study, I use transposon-insertion …
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CRISPRI-based high-throughput functional genomic approaches for use in mycobacteria
… to understanding the functional genome, such as transposon-insertion sequencing, have been developed and applied to mycobacteria in a variety of conditions; however, they have several limitations, particularly in their ability to study genes essential for viability. The recent optimisation of …
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Inquiries into the Mycobacterial Caseinolytic Protease System
… to this adaptability and pathogenicity. Previous transposon insertion sequencing (TnSeq) screens, in conjunction with our laboratory's work on mycobacterial genetic vulnerability, identified the caseinolytic protease (Clp) system, a central component of the proteostasis network, as essential and …