Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Transplantation Therapy"”.
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Reprogramming cellular fate using defined factors
… the need for immunosuppressants following cell transplantation therapy. It was recently reported that the forced expression of four transcription factors, Oct4, Sox2, c-Myc and Klf4 can induce a pluripotent state in somatic cells, without the need for embryo destruction. The work presented here …
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A Comparative Analysis of the Neurochemical Properties of Olfactory Ensheathing Cells and their Biocompatibility in Various Biomatrices
… OECs have been targeted as a potential cellular transplantation therapy for spinal cord injury. In order to effectively isolate OECs for intraspinal transplantation, more knowledge must be gained on their phenotypic properties. We investigated the neurochemical features of OECs in a variety of …
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Promotion and control of angiogenic activity in poly(ethylene glycol) diacrylate hydrogels for tissue engineering applications
… greatly needed biological organs and tissues for transplantation therapy. In living tissues of physiologically relevant size, metabolically active cells far from a nutrient source undergo necrosis when starved of oxygen and vital nutrients, but the incorporation of microvasculature would allow the …
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Towards cell replacement therapy in Parkinson’s disease. Proteoglycans and Nogo-A as modulators of axonal growth in midbrain dopaminergic neurons
… warranted. The concept of cell replacement therapy in PD is based on the idea that the diminished dopamine levels in the striatum would be restored by the functional DNs, obtained from donated, electively aborted fetuses, and subsequently injected into the patients’ striatum. In several …
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Development of a stem cell-based therapy for the recovery of skeletal muscle mass following immobilization
… rehabilitation is the most commonly prescribed therapy to help recover from disuse atrophy; however, illness and lack of mobility may limit physical activity and full recovery may not be possible, particularly in older adults. Therefore, there is a need to develop novel and more effective …
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Neural stem cell grafts and the influence of apolipoprotein E in a mouse model of global ischaemia
Neural stem cell (NSC) transplantation is a promising therapy for the treatment of brain damage. Although the “proof of principle” for NSC transplantation therapy has been demonstrated in a variety of animal models of brain injury (stroke, traumatic brain injury, ageing) and in a clinical setting …