Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"Transmucosal"”.
-
Preparation and Characterization of Lyophilized Cyclodextrin Complexes of a Hemisuccinate Ester of Delta-9-Tetrahydrocannabinol for Transmucosal Delivery
… metabolism. Our strategy towards developing THC transmucosal formulations involved development of hydrophilic prodrugs of THC and solubilization and stabilization of prodrugs in oral formulations. In the present study, the hemisuccinate ester of THC (THC-HS) has been investigated for its …
-
Receptor Mediated Oral Delivery Of Bioencapsulated Green Fluorescent Protein Expressed In Transgenic Chloroplasts
… oral delivery of therapeutic proteins using the transmucosal carrier cholera toxin B subunit (CTB), a CTB-GFP fusion protein separated by a furin cleavage site was expressed via the tobacco chloroplast genome and used as a visible marker. Site specific integration of the transgene was confirmed …
-
The Effect of Corticision on The Rate of Orthodontic Tooth Movement in Rats
… has been introduced, which consists of transmucosal manipulation of the alveolar bone with a scalpel incision without flap reflection.</p> <p>Since any manipulation of alveolar bone can potentially increase RAP and hence accelerate bone remodeling, we hypothesize that corticision will …
-
ANAESTHESIA AND PAIN MANAGEMENT IN COMPANION ANIMALS
… management was achieved in dogs receiving oral transmucosal cannabidiol oil in addition to a multimodal pharmacological approach for treatment of osteoarthritis-related pain in dogs. Combined with an anti-inflammatory drug, gabapentin and amitriptyline, cannabidiol appears to enhance …
-
IMPIANTI POST ESTRATTIVI IN SITI INFETTI: PROPOSTA DI UNA NUOVA METODICA DI TRATTAMENTO
… included in the present study. A total of 61 transmucosal implants were installed immediately after extraction and careful debridement combined with PRGF placement into the socket. Before insertion, the implant surface was bioactivated by humidification with liquid PRGFs. The prosthetic phase …
-
Design and evaluation of novel microencapsulation technologies to enhance delivery of Ciclosporin
… administer drug through the mouth, the skin, transmucosal areas, inhalation or injection. However, one of the current challenges is the lack of effective and targeted oral drug administration. Development of sophisticated strategies, such as micro- and nanotechnology that can integrate the …
-
Best antibiotics for buccal delivery
… The administration of drugs by transdermal or transmucosal routes are relatively painless, offers patients more choices, and reduces the need to establish intravenous access, which is a particular benefit for children and elderly. These alternative methods also provide clinical care providers …
-
Single dose pharmacokinetics of pimobendan in healthy horses
… and other species. There was no evidence of oral transmucosal absorption. Pimobendan was poorly absorbed in horses, regardless of formulation, and appears unlikely to have clinical effects.
-
Characterization of different hydrophilic polymers and their applicability in hot melt extrusion technology
… nasal, injection/implant, transdermal/dermal, transmucosal etc. for their potential to transport a variety of small and large drug molecules. In the present research work, oral route, a widely accepted route of administration, for the delivery of products with a major market share, has been …
-
Solubility enhancement, mechanical properties and taste masking of poorly water soluble compounds by optimizing hot melt extrusion processing
… have explored oral, nasal, dermal, transdermal, transmucosal, pulmonary, and injection routes for their ability to deliver large and small drug molecules. This research project focuses on the oral route, which is generally accepted as an effective delivery route for many drug products with a …
-
Novel polyelectrolyte complexes for oral insulin delivery.
Oral delivery of insulin used for the management of Type 1 diabetes could be referred to as one of the major long-term goals of diabetes research. However, the bioavailability of orally-administrered insulin is significantly compromised by enzymatic degradation in the GI tract, and poor enteral …