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Showing 1 to 1 of 1 for “"Translocation Capture Sequencing (TC-Seq)"”.

  1. The Extent and Nature Of Chromosomal Rearrangements in B Lymphocytes

    Klein, Isaac Andrew

    <p>Chromosomal rearrangements, including translocations, require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and are frequently involved in producing leukemias, lymphomas and sarcomas. Mature B cell lymphomas are unique among tumors in …

    rockefeller Repository record