Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Translin"”.
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Entwicklung und Anwendung eines Expressionsklonierungssystems in primären Kardiomyozyten - Identifizierung von Translin als neuem Target der Herzinsuffizienz
… system in primary cardiomyocytes - Validation of Translin as a new target for heart failure Congestive heart failure continues to represent a life threatening disease with unmet medical need. Functional impairment of the insufficient heart is reflected in altered geometry of the left ventricle. On …
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TB-RBP protein : sitting at the crossroads of sex and disease
… structure of TB-RBP in complex with Trax (translin associated factor X). Functions of TB-RBP is to suppresses translation of testicular mRNAs (Ex: protamines 1 and 2), attach mRNAs to microtubules for cellular transport of brain mRNAs and to mediate both temporal and spatial expression of …
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A molecular genetic investigation of rhabdomyosarcoma
… studies (EMSA) confirm that these sequences bind translin. These findings suggest that translin may not only be important in the genesis of chromosomal trartslocations in lymphoid malignancy, but also in translocations found in solid tumours. Mutation analysis of tumour samples and cell lines from …
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Regulatory Mechanism of the RNAi Pathway
… (component 3 promoter of RISC), a complex of Translin and Trax. C3PO is a novel Mg2+ -dependent endoribonuclease that promotes RISC activation by removing the siRNA passenger strand cleavage products. Similar as Drosophila C3PO, human C3PO also degrades passenger strand fragments and …