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Showing 1 to 7 of 7 for “"Translational fidelity"”.

  1. Orthogonal pair-directed codon reassignment as a tool for evaluating the factors affecting translation in E. coli

    … codon-anticodon binding energy in determining translational fidelity. Quantitative sense codon reassignment efficiency measurements showed that the process of translation is highly balanced and both tRNA abundance and aminoacylation efficiency do not appear to be dominant factors in determining …

    colostate Repository record for Orthogonal pair-directed codon reassignment as a tool for evaluating the factors affecting translation in E. coli (opens in a new tab)

  2. Multilayered regulation of translation: roles of rRNA modifications, alternative initiation factors, and RNA-binding proteins

    … entry site mediated translation, and compromises translational fidelity. Finally, the intrinsically disordered RNA-binding protein Sbp1 is examined for its role in translational regulation and mRNA storage. Our findings indicate that Sbp1 modulates translation efficiency and participates in mRNA …

    uiuc Repository record for Multilayered regulation of translation: roles of rRNA modifications, alternative initiation factors, and RNA-binding proteins (opens in a new tab)

  3. Enzymatic Characterization Of The Ammonia Tunnel In Helicobacter Pylori Asp-Trnaasn/glu-Trnagln Amidotransferase

    … important roles in indirect aminoacylation and translational fidelity; however, its inter-domain communication and ammonia delivery mechanisms are not well understood. In the present study, we investigated the three activities of <i>H. pylori</i> AdT (glutaminase, kinase and transamidase) and …

    wayne-thes Repository record for Enzymatic Characterization Of The Ammonia Tunnel In Helicobacter Pylori Asp-Trnaasn/glu-Trnagln Amidotransferase (opens in a new tab)

  4. The Role of tRNA methyltransferases in Cancer

    … modifications play a crucial role in maintaining translational fidelity and supporting cancer cell survival under adverse conditions. This thesis explores the contribution of two tRNA methyltrans- ferases - TRMT1, responsible for catalysing the m2,2G modification at position 26 in tRNAs, and the …

    cambridge Repository record for The Role of tRNA methyltransferases in Cancer (opens in a new tab)

  5. Ευκαρυωτική πρωτεϊνοσύνθεση σε αγρίου τύπου και μεταλλαγμένα ριβοσώματα ζύμης με την χρήση συνθετικών mRNA και η αναστολή της από αντιβιοτικά

    Στην παρούσα διατριβή μελετήθηκε ο ρόλος της έλικας h44 του 18S rRNA του Saccharomyces cerevisiae επί διαφόρων παραμέτρων της πρωτεϊνικής σύνθεσης. Η μελέτη διεξήχθη με την βοήθεια των σημειακών μεταλλάξεων A1491G (rdn15) και U1495C (rdnhyg1), οι οποίες εντοπίζονται στην Α-θέση του ριβοσώματος. Η …

    patras-thes Repository record for Ευκαρυωτική πρωτεϊνοσύνθεση σε αγρίου τύπου και μεταλλαγμένα ριβοσώματα ζύμης με την χρήση συνθετικών mRNA και η αναστολή της από αντιβιοτικά (opens in a new tab)