Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"Transient receptor potential channels"”.
-
Role of transient receptor potential channels in mammalian oviduct and uterine epithelia
… cells is either via tight junctions or calcium channels, specifically, members of the transient receptor potential (TRP) channel superfamily and the Na+/Ca2+ exchanger. TRP channels are an important class of calcium channels with more than 28 identified members and their potential involvement in …
-
Role of the Transient Receptor Potential Channels in Modulating Prefrontal Cortical Excitability and the Behavioral Responses to Cocaine
… a prolonged depolarizing response to Gq-coupled receptor activation, which produces a period of heightened excitability of the cell following brief bursts of action potential activity. This burst triggered delayed depolarization enables the cell to convert subthreshold inputs into persistent …
-
Chemesthesis in the Earthworm, Lumbricus terrestris: The search for TRP Channels
Chemesthesis is the chemical stimulation of receptors on somatosensory neurons usually by noxious chemicals leading to irritation. Transient receptor potential channels play a major role in detecting chemesthetic stimuli and are found in a wide variety of organisms, from yeast to humans. Currently, …
-
Effects of Chronic Oxidative Stress on TRPM2 and TRPC3 Channels: Potential Implications for Bipolar Disorder
… of these disturbances is unknown. The transient receptor potential (TRP) melastatin subtype 2 (TRPM2) and canonical subtype 3 (TRPC3) calcium-permeable non-selective ion channels, already implicated in BD, are involved in calcium and oxidative stress signalling. Thus, I sought to …
-
TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
… cells preferentially require certain ion channels and transporters for growth and survival. I thus screened ion channels and transporters throughout the genome to identify those required by human melanoma cells but not by normal human melanocytes. I discovered that Mucolipin-1 (MCOLN1), …
-
Characterization of Host Factors Affecting Viral Entry
The file named "RINKENBERGER-DISSERTATION-2019.pdf" is the primary dissertation file. Two (2) supplemental video files are also available and may be viewed individually.