Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1321 for “"Transgenic"”.
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Telepresence and Transgenic Art
Telepresence and Transgenic Art is an exploration of issues surrounding, on the one hand, the coupling of telematic networks with robotics and biology, and on the other, the exploration of genetic engineering, as an art medium. The integration between telepresence and genetic engineering is also …
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Lycopene metabolism in transgenic mice
Carotenoids are commonly consumed in the diet and are reported to have a wide range of bioactivities that can confer positive health benefits. The non-provitamin A carotenoid, lycopene, has shown to be one of the most abundant carotenoids in serum and is correlated with a wide range of health …
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Promoter analysis in transgenic sugar beet
… regulation of expression of foreign genes in the transgenic plants. A strategy has been defined for production of high sucrose yield ! high juice purity / low environmental impact varieties of sugar beet. This requires modification of the phytohormone levels in the outer cambial rings of the …
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Transgenic Insecticidal Corn and Coleomegilla Maculata
… bred hybrid that expresses mir 1, and transgenic hybrids that expressed Cry1Ab or Cry3Bb1) did not influence the fitness of C. maculata in the laboratory. This observation is in spite of the reduced quality of prey fed some of the insect-resistant hybrids. Finally, we observed that …
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Transgenic manipulation of polyamine metabolism in poplar
… under the control of 2X 35S CaMV promoter. The transgenic cells (line 2E) showed elevated levels of mouse ornithine decarboxylase enzyme activity, several fold higher amounts of putrescine, a small increase in spermidine, and a small reduction in spermine as compared with non-transgenic (NT) …
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Evaluation of transgenic, Bt-containing corn hybrids
… biotechnology have provided the tools to produce transgenic plants. Transgenic corn hybrids containing a modified Bacillus thuringiensis (Bt) gene have been produced and may provide a new method of managing ECB.
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Immunomodulation of Flavonoid Biosynthesis in Transgenic Arabidopsis thaliana
… vector, which was subsequently used to generate transgenic plants. One transgenic line with low expression of one of the scFv's appeared to have an altered flavonoid metabolism, as evidenced by a reduced capacity for anthocyanin accumulation and a reduction in flavonol glycosides in seedlings. …
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Evaluation Of Immunogenicity Of Transgenic Chloroplast Derived Protect
… concern is whether the PA83 purified from transgenic chloroplasts is as immunogenic as the PA83 in the AVA. For this, PA83 has been expressed in transgenic chloroplasts of Nicotiana tabacum var. petit Havana, by inserting the pag (2205 bp) with the N-terminal 6X histidine tag, into the …
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Expression of atrial natriuretic factor in transgenic potatoes
… rat atrial natriuretic factor, ANF-(1-126), in transgenic potatoes (Solanum tuberosum L. cultivar Iwa). Four ANF gene fusions were constructed for extracellular expression of ANF-(1-126) either by retaining the native signal peptide of ANF or replacing it with the secretory signal of a …
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Development of inducible transgenic mouse models for melanoma
… the purpose of this project was to establish a transgenic mouse model able to investigate the molecular mechanism(s) of melanoma aetiology mediated by N-Ras and PTEN genes. To achieve this, an inducible gene switch approach was employed exploiting the Cre/loxP recombinase system. This approach …
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Characterisation of transgenic mouse models of Alzheimer's disease
A number of transgenic mouse models have been developed to study the molecular and pathological alterations associated with Alzheimer’s disease (AD). The 3xTg mouse is widely used as a research tool and carries mutations in the amyloid precursor protein (Swedish APP K670N/M671L), presenilin 1 …
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Modeling insect resistance to transgenic corn and cowpea
… to protect the efficacy of commercial transgenic crops expressing Bacillus thuringiensis toxins because the benefits of the pest susceptibility to Bt toxins is considered as a common good. Simulation models have helped guide the USEPA’s regulatory decisions on the IRM requirements of …
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Modelling prion-induced neurodegeneration in PrP transgenic Drosophila
… of my thesis was to develop and characterise PrP transgenic Drosophila melanogaster of various genotypes to study the process of prion-induced neurodegeneration in this model. Prion diseases are caused by the occurrence of an abnormally-folded form of PrP (PrPSc) protein that arises either from …
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Expression of Human Protein C in Transgenic Tobacco
… The overall goal of the research was to develop transgenic plants that express hPC at higher levels. A cDNA encoding hPC was fused to an enhanced constitutive 35S promoter (35SDE ) and introduced into a plant transformation vector. The hPC construct was introduced into tobacco leaf disks using …
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Polyamine metabolism in Arabidopsis: Transgenic manipulation and gene expression
… Spermidine and Spermine) in wild type and transgenic Arabidopsis thaliana (Col 0 ecotype) plants was studied using the techniques of transgenic manipulation and gene expression. Two specific objectives were: (1) To study the effects of inducible and constitutive transgenic manipulation of …
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Controlled ablation of rod photoreceptors in transgenic Xenopus laevis
… of rod cell death in the retina, we generated transgenic X. laevis that expressed a novel form of caspase-9, with binding domains specific to the compound AP20187. We treated these transgenic animals with AP20187 and caused rod cell death by apoptosis in tadpoles and post metamorphic animals. …
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Transgenic Plants, Current State, and Influence on the Environment
… cells. Public concerns about the impact that transgenic plant might have on the environment have partly slowed down the large-scale use of transgenic plants. These concerns are discussed. Some suggestions regarding the releasing of the transgenic plant under field conditions are also discussed.
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Transgenic complementation of rumpshaker with wild type proteolipid protein
… we sought to ameliorate the lethal phenotype by transgenic complementation with wild type Plp1 (Readhead et al., 1994) to normalise the levels of proteolipid protein (PLP) and it’s smaller isoform DM20. The presence of the wild type protein improves the survival of the mice, decreases …
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Purification of an acidic recombinant protein from transgenic tobacco
… recombinant β-glucuronidase (rGUS), from transgenic tobacco leaf tissue to high yield and purity. Polyelectrolyte precipitation with polyethyleneimine (PEI) was identified as an initial purification step for purifying acidic recombinant proteins from tobacco. Polyethyleneimine …
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