Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Transgenerational inheritance"”.
-
Investigating the Epigenetic Mechanism Behind Transgenerational Inheritance in Mice with Abnormal Folate Metabolism
… unclear. My thesis focuses on a mouse model of transgenerational inheritance in which folate metabolism is disrupted by a mutation in Methionine synthase reductase ($\it{Mtrr^gt}$). Remarkably, $\it{Mtrr^+/gt}$ heterozygosity leads to an increased likelihood of a wide spectrum of congenital …
-
Programming of the paternal nucleus for embryonic development
… important contributions to the emerging field of transgenerational inheritance of epigenetic traits in general.
-
Multigenerational Neurobehavioural and Reproductive Toxicity of Arsenic in Zebrafish (Danio rerio)
… epigenetic alterations, and lineage-dependent inheritance patterns. In the first study (Chapter 2), adult zebrafish were exposed to environmentally relevant dietary arsenic concentrations (30, 60, and 100 µg/g dry weight, as arsenite) for 60 days. A latent learning assay demonstrated …
-
Intergenerational and Transgenerational Effects of Endocrine Insults
… of acquired traits to descendants. Such inheritance may be intergenerational or transgenerational, the latter describing effects that persist in the absence of any exposure (either directly or of parental germ cells) to the triggering environment. Numerous reports of non-genetic …