Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Transgenerational effects"”.
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Intergenerational and Transgenerational Effects of Endocrine Insults
… Such inheritance may be intergenerational or transgenerational, the latter describing effects that persist in the absence of any exposure (either directly or of parental germ cells) to the triggering environment. Numerous reports of non-genetic inheritance ascribe it to epigenetic mechanisms, …
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Transgenerational Effects of Maternal Age on Offspring Fitness in Crickets
… that can have both positive and negative effects on offspring fitness, and thus, parental age can be considered a parental effect. As a parental effect, parental age may affect a variety of offspring traits and may cascade to influence several generations of offspring. Given the …
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The transgenerational effects of Di(2-ethylhexyl) phthalate on female reproduction in mice
… but even more troubling is that some of the effects of DEHP may be multigenerational or transgenerational in nature. To obtain a multigenerational or transgenerational effect, the phenotype or the effect must be passed from one generation to a subsequent generation. During prenatal exposure, …
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Transgenerational Effects of Synthetic Glucocorticoids on Offspring Behaviour and HPA Development in Guinea Pigs
… results in transmission of HPA and behavioural effects to the next generation (F2) of offspring, but no study has investigated transmission to the third generation (F3). We hypothesized that prenatal treatment with sGC results in maternal and paternal transmission of altered HPA activity and …
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An integrative analysis of the multi- and transgenerational effects of endocrine-disrupting chemicals on behavior and neurobiology
… and dysfunction later in life. Furthermore, EDC effects have been reported in individuals several generations removed from the initial exposure. In this dissertation, I investigated the effects of preconceptional (F2 germ cell) exposure to EDCs, and the potential mechanisms by which these effects …
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Investigating factors within the parental environment that influence the fitness of a freshwater gastropod species and their sensitivity to metal exposure
… data must accurately represent the adverse effects that may occur in environmentally relevant exposure scenarios. An increasing weight of evidence suggests that certain chemicals can cause lasting adverse outcomes on populations long after the initial exposure had ended. These latent or …
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Reframing as Reclamation: Trauma Theory, African Spiritualism, and Ecocriticism in Jesmyn Ward’s Sing, Unburied, Sing
… of collective healing. Trauma, and its subset transgenerational trauma, have often been a focal point for critical analysis of other African American texts that engage with ghosts and hauntings, such as Toni Morrison’s <em>Beloved</em> (1987). Often, these ghosts are symbolic of …
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Morphologische Plastizität
… last embryonic stage. Induction experiments on transgenerational effects in Daphnia cucullata show that defended mothers release offspring that are better defended than the descendants of unthreatened parents. Furthermore, daphnids could asses their actual predation risk by taking both predator …
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The effects of an environmentally relevant phthalate mixture on female reproduction
… Very limited information is available on the effects of phthalate mixtures on female reproduction, and even less information is available on the effects of an environmentally relevant phthalate mixture on female reproduction. Thus, the goal of my doctoral dissertation work was to examine the …
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LIQUID PLASTICS AS A NEW ENVIRONMENTAL PROBLEM? AN INTEGRATED RISK ASSESSMENT OF POLYVINYL ALCOHOL, POLYETHYLENE GLYCOL, POLYVINYL PYRROLIDONE AND POLYACRYLIC ACID
… on PVA standard, examining its acute and chronic effects on D. rerio and D. magna. Acute toxicity tests showed no significant effects at environmentally relevant concentrations, while chronic toxicity assessments revealed few behavioral changes in both D. magna and D. rerio, with slight …
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Long-term effects of insecticides on environmental health: How does exposure of a female egg-laying insect to an insecticide affect subsequent generations?
… target crops. Despite abundant research on the effects of insecticides on various aspects of the (target) insect life cycle, we know surprisingly little about any possible transgenerational effects, especially in beneficial non-targets. Such effects could be of concern in an environmental and …
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Chronic Impact Of Cerium Oxide Nanoparticles On Solanum Lycopersicum L. And Brassica Rapa L.
… The first objective was to investigate the effects of combined CeO2-NPs and TiO2-NPs exposure on tomato plant growth and oxidative stress. The second objective was to investigate the impact of a lifecycle exposure to CeO2-NPs on wild type tomato growth and fruit yield and to evaluate the …
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Paternal diet and exercise epigenetically program energy expenditure and glucose metabolism in mouse offspring
… investigations are now finding the detrimental effects of poor lifestyle choices, such as consuming a high-fat diet, have heritable consequences that persist transgenerationally by way of epigenetic modifications. The epigenome is yet another tier of genetic regulation, one that is capable of …
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Epigenetics, a signal sensor of dietary components, is involved in the hepatic gene regulation
… epigenetic regulation [4]. Although some transgenerational effects of high dietary fat intake have been shown in a couple of studies linked to certain types of epigenetic modulations [5-8]; these modifications and their associated physiological consequences resulting from high fat …
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Prenatal exposure to phthalates accelerates reproductive aging in multiple generations of female mice
… chemicals that can cause detrimental effects on reproduction in males and females. Specifically, in females, phthalates have been shown to accelerate primordial follicle recruitment, disrupt estrous cyclicity, inhibit ovarian steroidogenesis, and disrupt fertility. Furthermore, these …