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Showing 1 to 20 of 114 for “"Transferrin"”.

  1. Cleavage of exosomal-associated transferrin receptor in dogs, cats, and horses: progress towards a soluble transferrin receptor assay

    Martinez, Caitlyn Marisa Romero, author, Olver, Christine, advisor, Santangelo, Kelly, advisor, Duval, Dawn, committee memberColorado State University. Libraries2018

    … disease or the other. In human medicine, soluble transferrin receptor 1 (sTfR) has shown promise as a marker, alone or in ratio with serum ferritin, that can differentiate iron deficiency anemia, anemia of chronic disease, and combined disease. sTfR is the product of cleavage of transferrin …

    colostate Repository record

  2. Initial Crystallographic Analysis Of Human Serum Transferrin.

    Delucas, Lawrence James

    uab Repository record

  3. Mini-Isoelektrofokussierung von Serum-Transferrin bei Patienten mit CDG-Syndrom

    Wiescher, ChristinaLudwig-Maximilians-Universität

    … eine Methode zur Isoelektrofokussierung von Transferrin entwickelt. Die IEF im Mini-PhastSystem ist hier besonders schnell und zuverlässig. Die charakteristischen Bandenmuster des mit einer verminderten Anzahl an Sialinsäureresten glykosylierten Transferrins liefern erste …

    lmu-germany Repository record

  4. A study of transferrin and iron in chronic skin wounds

    Dorsey, William Kevin1997

    This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).

    iupui Repository record

  5. Metal binding to transferrin and immune reactions in Parkinson's disease

    Winsper, Sarah J.Aston University1995

    … (59Fe) and gallium (67Ga) to the plasma protein transferrin (Tf) was investigated by G75 gel filtration chromatography in control patients and treated and untreated patients with Parkinson's disease (PD). Fe-Tf binding was 100% in all controls and PD patients suggesting that a defect in Fe-Tf …

    aston Repository record

  6. A Transferrin conjugated nanoemulsion system for brain delivery of antiretroviral therapy

    Si, MengjieTemple University. Libraries2019

    … The goal of this study is to develop a new transferrin conjugated nanoemulsion system (Tf-NE) for antiretroviral medication delivery and evaluate its potential to cross the BBB. Nanoemulsions were prepared based on the solvent evaporation sonication method using lipids and phospholipids. To …

    temple Repository record

  7. Transferrin binding protein B structure, function, and export in Neisseria gonorrhoeae

    Weck, Meredith L.2017

    … iron-binding proteins, such as lactoferrin and transferrin. Neisseria gonorrhoeae utilizes transferrin as an iron source and its iron acquisition system is composed of two transferrin binding proteins: TbpA and TbpB. TbpA is a TonB-dependent, outer membrane transporter and TbpB is a bilobed, …

    vcu Repository record

  8. SPECTROSCOPIC STUDIES OF THE INTERACTION OF ANIONS WITH TRANSFERRIN (NMR, PYROPHOSPHATE)

    SWOPE, SUSAN KEENE

    <p>Kinetic studies of the uptake of iron by transferrin from iron-pyrophosphate indicate that the reaction proceeds via an intermediate mixed ligand complex of the type PP(,i)-Fe-transferrin-CO(,3)('2-). The EPR spectrum of the "intermediate" complex was determined by computer modelling of the …

    unh-thes Repository record

  9. Studies on the role of hephaestin and transferrin in iron transport

    Hudson, David M.University of British Columbia2008

    … into blood. These ferroxidases supply transferrin, the iron-carrier protein in plasma, with Fe(III). Transferrin circulates through blood and delivers iron to cells via the transferrin receptor pathway. Due to the insoluble and reactive nature of free Fe(III), the oxidation of Fe(II) …

    ubc Repository record

  10. Recombinant expression of human serum transferrin in escherichia coli and pichia pastoris

    Steinlein, Lauren MarieGeorgia Institute of Technology1996

    gatech Repository record

  11. The Role of Ferritin and Transferrin Receptor in Oligodendrocyte Maturation and Myelination

    Wan, RenshengState University of New York at Buffalo2019

    M.S.

    buffalo Repository record

  12. A STUDY OF THE THERMODYNAMICS OF ANION BINDING TO HUMAN SERUM TRANSFERRIN

    FOLAJTAR, DONALD ALLEN

    … difference spectroscopy of diferric human serum transferrin indicates that certain inorganic anions alter the electronic environment of the ion centers of the protein by binding to specific anion sites. The binding of these anions (thiocyanate, perchlorate, adenosinetriphosphate, pyrophosphate, …

    unh-thes Repository record

  13. Deciphering the mechanism of Transferrin Receptor mRNA degradation under iron replete conditions

    Rupani, Dhwani2016

    … controlled. For most cells in the body, the transferrin receptor (TFRC-1) is the major means through which iron is imported into the cell. Influx of transferrin bound iron is regulated by changes in the stability of TFRC-1 mRNA. Under iron deplete conditions, iron regulatory proteins 1 and 2 …

    umn Repository record

  14. Design of folic acid, transferrin, and integrin receptor specific polyamidoamine dendrimers for gene delivery

    Hwang, MarkUniversity of Illinois at Urbana-Champaign2012

    Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2012-06-14T15:37:18Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 2 Hwang_Mark.doc: 55420928 bytes, checksum: 0010b064d38a25a15d06deb51af67ca4 (MD5) Hwang_Mark.pdf: 22852276 bytes, checksum: …

    uiuc Repository record

  15. Structure of the trypanosome transferrin receptor and insights into ligand binding and therapeutic strategies

    Trevor, Camilla ElizabethUniversity of Cambridge2020

    … whilst also avoiding immune detection. Host transferrin (Tf) is acquired by trypanosomes through the expression of a transferrin receptor (TfR), which does not share homology with the host TfR. Multiple diverse copies of the TfR are present in the trypanosome genome but only one is expressed …

    cambridge Repository record

  16. Investigation of the Immunogenicity and Specificity of the Transferrin Binding Proteins from Bovine Pathogenic Bacteria

    Pogoutse, Anastassia Igorevna2019

    … that does not support microbial proliferation. Transferrin is a bilobal iron carrying protein found in the blood and cerebrospinal fluid, and on mucosal surfaces. It is targeted by a number of microbial transferrin binding proteins and siderophores. This thesis focuses on one of the best-studied …

    toronto-retro Repository record

  17. Study of a Transferrin Receptor Brain Shuttle for the Delivery of Nanobodies Against GABAA Receptors

    King, OliverUniversity of Cambridge2024

    … targeting receptors present at the BBB, such as transferrin receptor (TfR), hijacking endogenous trafficking systems to shuttle conjugated therapeutic cargo from the blood circulation into the brain parenchyma. Such systems could be utilised to improve the delivery of novel immunogenically-raised …

    cambridge Repository record

  18. KINETIC, SPECTROSCOPIC AND CHEMICAL MODIFICATION STUDY OF IRON RELEASE FROM TRANSFERRIN; IRON(III) COMPLEXATION TO ADENOSINE TRIPHOSPHATE (ETHOXYFORMIC ANHYDRIDE, LYSINE)

    THOMPSON, CARL PERLEY

    … found to influence the chemical properties of transferrin iron. The catalytic ability of pyrophosphate to mediate transferrin iron release to a terminal acceptor is largely quenched by modification non-liganded histidine groups on the protein. The first order rate constants of iron release for …

    unh-thes Repository record

  19. Novel non-viral delivery systems for cancer gene therapy

    Kewcharoenvong, PaphitchayaUniversity of Strathclyde2016

    … Conjugation of targeting ligands such as transferrin and lactoferrin is an attractive tool to improve specificity and cellular uptake of carriers, and surface modification of dendrimers with hydrophilic polymers such as polyethylene glycol should facilitate lower systemic toxicity and …

    strathclyde Repository record

  20. Optimisation of the anti-cancer efficacy of various tocotrienol isomers by entrapment in tumour-targeted vesicles

    Karim, ReatulUniversity of Strathclyde2013

    … that tocotrienol-rich fraction entrapped in transferrin-bearing vesicles led to an increased therapeutic efficacy in vitro and in vivo on mice, compared to the drug solution. This formulation may be further improved by entrapping only the most effective tocotrienol isomer within the optimised …

    strathclyde Repository record

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