Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Transcriptional enhancers"”.
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Multiple regulatory layers in the establishment of Rbfox2 splicing networks
… We also investigated mechanisms of co-transcriptional splicing regulation by Rbfox2. Using chromatin immunoprecipitation, we found that Rbfox2 is recruited early in the transcription cycle to active promoters and transcriptional enhancers, likely via interaction and co-transcriptional …
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Genetic Regulation of Müllerian Duct Regression
… illuminated an apparent a lack of known enhancers for genes active in the MD mesenchyme. To identify the MD mesenchyme specific transcriptional enhancers, we utilized bacterial artificial chromosome (BAC) transgenic mice. <em>Osx</em> and <em>Amhr2</em> are two genes expressed in the MD …
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A Semi-Supervised Predictive Model to Link Regulatory Regions to Their Target Genes
… and polyadenylation are presented.</p><p>Transcriptional enhancers are specific DNA sequences that act as ``information integration hubs" to confer regulatory requirements on a given cell. These non-coding DNA sequences can regulate genes from long distances, or across chromosomes, and …
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Targeted Deletion of Functionally Validated Enhancers Defines Their Role In Mouse Limb Development
<p>Transcriptional enhancers are genomic DNA sequences that contain clustered transcription factor (TF) binding sites. When combinations of TFs bind to enhancer sequences they act together with basal transcriptional machinery to regulate the timing, location and quantity of gene transcription. …