Global ETD Search
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Showing 1 to 2 of 2 for “"Transcriptional Module"”.
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On single-cell immune dynamics of chronic HIV infection and treatment in rhesus macaque models
… gene expression and enrichment. I further link transcriptional changes to intact proviral burden and identified ribosomal pathways as markers infection stage, treatment status, reservoir size. Finally, by evaluating published immune correlates of treatment outcome, I identify nuances in …
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Computational Dissection of Composite Molecular Signatures and Transcriptional Modules
… dissection of molecular signatures and transcriptional modules. The first part of the dissertation is focused on extracting pure gene expression signals from tissue or cell mixtures. The main goal of gene expression profiling is to identify the pure signatures of different cell types …