Global ETD Search
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Showing 1 to 2 of 2 for “"Transcription silencing"”.
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Characterising the interaction between TRIM28 and members of the Krab-ZFP family in transcription silencing
… embryogenesis, largely through TRIM28-mediated transcription repression. TRIM28 (also known as KAP1 or TIF1β) functions as the co-repressor protein for the largest family of transcription factors, namely the Krüppel-associated box-containing zinc finger proteins (Krab-ZFPs). Silencing is …
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Phopsphorylation and Ubiquitin Modification At Dna Damage Sites In Response to Double-Strand Breaks
… manner that is essential for inhibiting transcriptional silencing at proximity to DSB sites to maintain genomic stability. Overall, my findings provide insights into how post-translational modifications regulate DDR factors dynamics at DSB sites and play a crucial role in maintaining …