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Showing 1 to 2 of 2 for “"Transcription Factor Specificity"”.

  1. Quantitative Analysis Demonstrates Most Transcription Factors Require only Simple Models of Specificity

    … cues. A key part of this process is transcriptional regulation, which is largely accomplished by a complex network of transcription factor proteins: TFs) interact with their specific binding sites in the genome. Understanding how TFs select correct binding sites out of the vast number …

    wustl Repository record for Quantitative Analysis Demonstrates Most Transcription Factors Require only Simple Models of Specificity (opens in a new tab)

  2. Targeted Inhibition of Sp1 Transcription Factor and Anti-Angiogenesis of Human Pancreatic Cancer

    <p>Transcription factor Specificity Protein 1(Sp1) is reported to be essential for vascular endothelial growth factor (VEGF) constitutive expression in human pancreatic adenocarcinoma. The definitive role of Sp1 in angiogenesis, the impact of anti-angiogenic therapy on the Sp1/ VEGF signaling and …

    uthsc Repository record for Targeted Inhibition of Sp1 Transcription Factor and Anti-Angiogenesis of Human Pancreatic Cancer (opens in a new tab)