Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Transcription Elongation, Genetic"”.
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Chemical Genetic and Genomic Discovery of PARP-1-Dependent Mechansims of Transcriptional Regulation
… II, implicating PARP-1 in RNA Polymerase II elongation through ADP-ribosylation and inhibition of NELF. PARP-1 is activated by both DNA lesions and nucleosomally wrapped DNA, the latter of which is a likely substrate for PARP-1 in its role as a regulator of transcription. In order to identify …
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Enzymatic Disassembly of Promoter Bound 7SK snRNP Drives Transcription Elongation of HIV and Cellular Genes
… genes (PRG’s) is regulated at the step of transcription elongation. Shortly after transcription initiation, RNA Polymerase II (Pol II) pauses and it only enters into productive elongation after inducible transcription factors (TF’s) recruit the P-TEFb kinase to phosphorylate Pol II in …