Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Transaortic constriction"”.
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Der Einfluss mechanischer Last auf das Potential multipotenter adulter Keimbahnstammzellen zur kardialen Regeneration
… Maus wurden durch aortocavale Shunt (Shunt)- und transaortic constriction (TAC)-Operationen etabliert. Vier Wochen nach der Shunt-OP zeigte die Myokardstruktur kaum Veränderungen, während die TAC-OP zu starken Veränderungen der Myokardstruktur und zu vermehrter Fibrose führte. Auch in Vorlast- und …
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Exploring the Role of Mitochondrial Bioenergetics and Metabolism in Heart Failure
… model and littermate controls were subjected to transaortic constriction, a surgical method to induce pressure-overload heart failure. The hyperacetylated animals did not exhibit enhanced sensitivity toward cardiac dysfunction relative controls. With these results, we concluded that mitochondrial …
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To Phosphorylate or Not to Phosphorylate: The Role of Tropomyosin Phosphorylation in Cardiac Function and Disease
… When α-Tm S283A TG animals are subjected to transaortic constriction (TAC), the TG TAC animals fail more quickly than the non-transgenic (NTG) TAC animals. In TG hearts, there is an increase in SERCA2a expression and an increase in PLN phosphorylation at Ser16. This increase in energetic …
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Physiological Role of the α<sub>2</sub>-Isoform of the Na, K-ATPase in the Regulation of Cardiovascular Function
… mice in response to pressure-overload induced by transaortic constriction (TAC), however the βMHCα<sub>2</sub><sup>-/-</sup> mice deteriorated to control levels by nine weeks post-TAC. </p><p>In summary, this dissertation refines the roles of the α<sub>2</sub>-isoform of the Na,K-ATPase in the …