Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Trans endothelial electrical resistance (TEER)"”.
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Brain microvascular endothelial cell dysfunction in schizophrenia: a preliminary report
… of schizophrenia (SZ). Brain microvascular endothelial cells (BMECs) have paracellular and transcellular proteins, transporters, as well as important extracellular matrix proteins, which collectively contribute to maintaining proper BBB function. While previous studies have provided some …
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Generation and Characterization of Human Blood-Brain Barrier Models for Investigating Neuropsychiatric Disorders and Tumor Metastasis
… disorders. The brain-specific microvascular endothelial cell (BMEC) is an essential structural component of the BBB. To test if integrity of the BBB formed by BMECs is compromised in 22q11.2 deletion syndrome (also called DiGeorge syndrome), which is one of the validated genetic risk factors …
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The role of the gut microbiota in the function and integrity of brain barriers
… footprint and barrier integrity measured by trans-endothelial electrical resistance (TEER). While we do not yet understand the dynamics of the BBB following acute stress, we know that microbial metabolites can interact with BBB function, so we next assessed the potential for acute-stress …
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New purinergic-based pharmacological targets for the treatment of retinal disorders
… model entirely based on human cells (retinal endothelial cells, retinal pericytes, and retinal astrocytes), in order to mimic the human milieu, characterized by the same cellular numerical ratio and layer order observed in vivo. The results obtained by using this innovate system showed that an …
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Evaluation of Novel Efflux Transport Inhibitor for the improvement of drug delivery through epithelial cell monolayer
… nervous system (CNS) and periphery. In mammals, endothelial cells were shown to be of BBB and are characterized by the tight junctions along with efflux system which are responsible for the restriction of movement of molecules within the cells. Efflux system consists of multidrug resistance …