Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 1099 for “"Trafficking"”.
-
Trafficking motifs in potassium channels
… is of fundamental importance to investigate the trafficking mechanisms that regulate the surface density of these channels. Techniques in cell biology, molecular biology and biochemistry were employed to identify the molecular basis of Sar1-GTPase dependent ER exit of the KATP and hERG channels …
-
Human Trafficking in Poland: Further Victimization of Female Victims of Human Trafficking for Sexual Exploitation
… destination, and transit country for human trafficking. The country is taking steps to address this crime, but it offers very little benefits to the victims. Currently, the victims are only allowed to stay temporarily in Poland if they testify against their traffickers. During their …
-
Study of sex trafficking in Namibia
… the existence, prevalence and causes of trafficking for sexual exploitation in Namibia, as well as its impact and effects on both its victims and society as a whole. Due to the complexity and dangerous nature of her topic of study, she utilised a unique method in which she identifies and …
-
Pathways to Offending: Domestic Sex Trafficking
… to understand the complex phenomenon of sex trafficking to assist victims, correct offenders, and prevent future abuse. However, current research has struggled to agree on terms, definitions of terms, best measures of prevalence, and recommendations to address sex trafficking in the United …
-
Human trafficking : women's stories of agency
… thesis is about women’s stories of agency in a trafficking experience. The idea of agency is a difficult concept to fathom, given the unscrupulous acts and exploitative practices which demarcate and define trafficking. In response to the three Ps of trafficking policy (prevention and protection …
-
Intracellular trafficking of Leishmania major peptidases
… not affect LMP localisation, suggesting that its trafficking is AP3-independent, which is in accordance with the non-lysosomal localisation of LMP. Finally, the lysosome-like acidocalcisome organelles have previously been shown to rely on the protein carrier complex AP3 for normal structure and …
-
Regulation of polarised trafficking by Klp98A
Directional trafficking of cargo, a hallmark of living cells, relies on a polarised landscape of microtubule tracks. Here, I studied how the regulation of an endosomal motor affects polarised trafficking, using the asymmetric division of *Drosophila* Sensory Organ Precursor (SOP) cells as a model …
-
Defining Success in Anti-Trafficking Policy: An Analysis of the U.S. State Departments Criteria for Combating Human Trafficking
Victims of human trafficking may be exploited for prostitution, sweatshop labor, domestic work, and as child soldiers for armed conflicts. According to the U.S. Department of Health and Human Services, "after drug dealing, human trafficking is tied with the illegal arms industry as the second …
-
The social construction of risk in child trafficking discourses: A study of melodramatic tactics in child trafficking narratives
Child trafficking is a term used to define situations where children are forced, coerced or tricked to migrate for the purpose of their future exploitation. The issue of child trafficking is a well established UK policy concern initially emerging in the seventeenth century. The issue re-appeared in …
-
Membrane trafficking of ATP-sensitive potassium channels
… cell surface into a perinuclear compartment. The trafficking itinerary of these channels has been found to include the sorting endosome, late endosome and elements of the trans-Golgi network. Upon inhibition of protein kinase-C activity the internalised channels are redirected into a pathway which …
-
Sphingomyelinases and Lysosomal Trafficking in Ebolavirus Entry
… EBOV, it appeared that this vesicle trafficking pathway was required for infection. During lysosomal exocytosis, pH-dependent acid sphingomyelinase (ASM) is released to the plasma membrane‟s outer leaflet, resulting in ASM-dependent macropinosome formation. Because EBOV enters via a …
-
Endosomal Trafficking and Exosomal Secretion of Egfrviii
… results reveal novel aspects of the endocytic trafficking of EGFRvIII that underlie its reduced degradation and the mechanism by which it is packaged into exosomes for secretion. Moreover, I show that EGFRvIII secretion on exosomes can facilitate changes in the tumor microenvironment to enable …
-
Cellular Trafficking of Single and Multistage Vectors
… we investigated the intra and inter cellular trafficking of the multistage system in endothelial cells bringing evidence of its bio-compatibility as well as its ability to perform multiple intra and inter cellular tasks. Once internalized in cells, the multi-particle construct is able to …
-
Dysfunction of ciliary vesicle trafficking in ciliopathies
Contains fulltext : 181326.pdf (Publisher’s version ) (Open Access)
-
Rab-domain dynamics in endocytic membrane trafficking
… not function in recycling,but appears to mediate trafficking between Golgi/TGN and endosomes instead.In order to address the dynamics of Rab-domains, fluorescently tagged Rab-GTPases were imaged during cargo transport reactions in living cells. Herefore high-speed/long-term imaging procedures and …
-
Manipulating PLGA nanoparticle cellular uptake and trafficking
… their cellular uptake and intracellular trafficking to a specific compartment inside the cell by modulating physicochemical properties i.e. size. Different sizes of Rhodamine-B conjugated PLGA NPs were synthesized and optimized to achieve the required sizes (< 100, ≈ 200, > 500 nm). …
-
Profilin II : novel functions in membrane trafficking
Profilin II - Novel functions in membrane-trafficking Ralph Gareus - EMBL Mouse Biology Programme, Monterotondo, Italy Profilin is an actin-binding protein expressed in all eukaryotic cells, regulating microfilament remodelling. Besides actin, it binds to poly-L-proline and phosphatidylinositol …
Page 1 of 55