Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 626 for “"Toxicology"”.
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Toxicology of phencyclidine
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Toxicology of endocrine disrupting chemicals
… to these substances. Articles related to the toxicology of EDCs were collected from the PubMed database. All reviews published within the last 10 years were studied. Relevant information was also collected from the website of the World Health Organization. Hundreds of natural and synthetic …
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The toxicology of sodium pentafluorostannite
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Toxicology of nanoparticles after cellular uptake
Nanoscience is a multi-disciplinary field with the potential to both create new applications and understand existent systems, but its materials may be sources of toxicological concern. Understanding their toxic potential becomes essential to prevent any occupational, environmental, and consumer …
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The epidemiology, pathology and toxicology of suicide
… of the world. The epidemiology, pathology and toxicology of complete suicides were investigated in this study. All the complete suicide cases, which were presented to Salt River Medicolegal Laboratory over a period of one year (1 January 1997 - 31 December 1997), were analysed. The candidate …
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The toxicology of nitric oxide In vitro
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1996.
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Towards Deep-Sea Toxicology: Experimental Approaches With Echinoderms
As anthropogenic activities expand into the deep sea, it is only recently that the importance of<br/>deep-sea ecosystems and processes to global biogeochemical systems has become clear. If the<br/>potential impact of human activity upon deep-sea organisms and ecosystems is to be understood<br/>and …
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Advancing Toxicology-Based Cancer Risk Assessment with Informatics
… informatics was effective in advancing toxicology-based cancer risk assessment using databases and predictive techniques which fill critical gaps in its methodology.
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Toxicology and pharmacology of N¹-acetylspermidine and N⁸-acetylspermidine
<p>The polyamines are a group of natural compounds which have been found in almost all living tissues. N<sup>1</sup>- and N<sup>8</sup>- acetylspermidine have been known for a considerable time as normal constituents in human urine, but their physiological role is unknown. Recent studies have …
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Macrophages in vitro as a predictive model in polymer toxicology
Organic polymers S2218600, S2429901 and S2219200 (referred to as Polymer 1, Polymer 2 and Polymer 3, respectively) of varying toxic potential, designed for use in cosmetic aerosols, were used as model substances to predict inflammatory potential. In vivo inflammogenic potential was evaluated by …
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A systems toxicology framework for improving the identification of paracetamol overdose
… sub-optimality. Within this thesis, a systems toxicology approach is taken in an attempt to provide further insight into the APAP overdose problem, and propose potential improvements to the current treatment framework. In Chapter 2, a proof-of-concept pre-clinical …
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The occurrence and toxicology of heavy metals in Chesapeake Bay waterfowl
The goals of this study were to elucidate relationships between food habits and tissue accumulations of heavy metals in Chesapeake Bay waterfowl and to determine effects of chronic cadmium and lead ingestion on energy metabolism in waterfowl. Concentrations of cadmium, lead, copper, and zinc were …
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Unique applications of cultured neuronal networks in pharmacology, toxicology, and basic neuroscience
… and drug development, biosensors and neurotoxicology, and the study of burst and synaptic mechanisms. Chapter 1 details the testing of seven novel AChE inhibitors, demonstrating that neuronal networks rapidly detect small molecular differences in closely related compounds, and reveal …
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New Developments in Analytical Toxicology for the Investigation of Drug Facilitated Crime
Drug facilitated assault (DFA) is an increasing problem in the UK. The crime often occurs through the surreptitious administration of a drug into a victims drink, rendering the victim unable to resist the assault. The detection of these drugs in a biological specimen from the victim is one of the …
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Cell Toxicology Study of RRR-Alpha-Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS).
<p>This research focused on the cytotoxic properties of RRR-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS) in transformed and cancerous cell lines. We used RAW264.7 macrophage and prostate cancer (LNCaP) cell lines in this study. TPGS caused cell death and decreased cell viability in a …
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Efficient Design Of Biological Experiments For Dose-Response Modeling In Nanomaterial Toxicology Studies
… Bayesian optimum design procedure in nanotoxicology with simulation experiments. The proposed design method adopts suitable nonlinear dose response curve and non-constant variance model in experimental modeling, which more adequately represents the desirable properties of …
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