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Showing 1 to 20 of 77 for “"Toxic effect"”.

  1. The combined toxic effect of nanoparticles and lead in the presence of algae (Raphidocelis)

    <p>"The elevated toxicity of toxic metals in the presence of nanoparticles (NPs) has raised significant concerns on the NP environmental safety. This research focuses on the impact of environmental conditions, specifically algae, on this type of toxicity. An indicator aquatic organism, …

    must-thes Repository record for The combined toxic effect of nanoparticles and lead in the presence of algae (Raphidocelis) (opens in a new tab)

  2. Endothelin-1 is over-expressed in Amyotrophic Lateral Sclerosis and induces Motor Neuron cell death

    … role in degeneration of MNs, we investigated its effect on MN survival in an in vitro model of mixed rat spinal cord cultures (MSCs) enriched of astrocytes exhibiting a reactive phenotype. ET-1 exerted a toxic effect on MNs in a time- and concentration-dependent manner, with an exposure to 100-200 …

    catania Repository record for Endothelin-1 is over-expressed in Amyotrophic Lateral Sclerosis and induces Motor Neuron cell death (opens in a new tab)

  3. Role of glutamate in lead-induced toxicity: protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant

    … a major public health problem, in the US today. Toxic effect of lead are mainly manifested in central nervous system (CNS) because brain acts as a reservoir for lead deposition. Lead-induced cell damage include glutamatergic component (excitotoxic cell damage arising from impaired clearance of …

    must-thes Repository record for Role of glutamate in lead-induced toxicity: protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant (opens in a new tab)

  4. Energy substrates, metabolic regulators, and lipid accumulation during culture of in vitro-produced bovine embryos

    … of embryos compared to the control. There was no effect of glucose or fructose on survival of embryos after cryopreservation by slow freezing or vitrification; however, embryos-treated with PES to reduce lipid content resulted in improved cryotolerance, and FCS decreased cryotolerance compared to …

    colostate Repository record for Energy substrates, metabolic regulators, and lipid accumulation during culture of in vitro-produced bovine embryos (opens in a new tab)

  5. Respuestas ecofisiológicas al enriquecimiento de amonio en angiospermas marinas

    … decline worldwide. One of the main negative effects is indirectly caused by the proliferation of fast-growing species promoting light attenuation, sediment anoxia and sulphide intrusion risks. However, the parallel direct toxic effect caused by high ammonium (NH4+) concentrations on …

    cadiz Repository record for Respuestas ecofisiológicas al enriquecimiento de amonio en angiospermas marinas (opens in a new tab)

  6. Release, Stability and Functionality of Nanodelivered Hydrophobic (Lutein and Beta-Carotene) and Hydrophilic (Folic Acid) Antioxidants Using Zein Nanoparticles

    … a good biocompatibility, and diminished the toxic effect of folic acid on cells. The increased uptake, particularly by the over-expressing folate-receptor cells indicated that zein nanoparticles can be developed into versatile targeted delivery systems. These findings strongly support the …

    lsu-thes Repository record for Release, Stability and Functionality of Nanodelivered Hydrophobic (Lutein and Beta-Carotene) and Hydrophilic (Folic Acid) Antioxidants Using Zein Nanoparticles (opens in a new tab)

  7. Investigations of the health benefits of buttermilk fat globule membrane lipid components

    … human colon cancer cells by 97.5% but had no toxic effect on FHC human normal colon cells as determined by the acid phosphatase cytotoxicity assay. Antiproliferative activity was lost after spray drying of buttermilk but was retained after heat treatment and freeze and spin drying. In contrast …

    dcu Repository record for Investigations of the health benefits of buttermilk fat globule membrane lipid components (opens in a new tab)

  8. Effect of Quantum Dots, Novel Biological Imaging Agents, in Liver Cells in Vitro

    … However, there are concerns regarding the toxic effects of QDs and the minimal dose that can be used without producing any detrimental effects to organisms. In this study, QDs coated with the amphiphilic polymer coating tri-n-octylphosphine oxide and poly (maleic anhydride-alt-1-tetradecene …

    central-wash Repository record for Effect of Quantum Dots, Novel Biological Imaging Agents, in Liver Cells in Vitro (opens in a new tab)

  9. The Role of S-Adenosylmethionine Synthetase in Killing Effects of DFMO in African Trypanosomes

    … the role of a functional AdoMetSyn in the toxic effect of eflornithine, a clinically used therapy for the treatment of the disease. Prior studies suggested that the toxicity of eflornithine may be due to the combined effect of polyamine depletion and detrimental effects of increased levels …

    utswmed Repository record for The Role of S-Adenosylmethionine Synthetase in Killing Effects of DFMO in African Trypanosomes (opens in a new tab)

  10. Mechanism Determination of the Effects of Pancratistatin on Model Mitochondrial Membranes

    … human cancer cell lines while having minimal/no toxic effect on normal cells. However, PST’s mechanism of action remains uncertain. To better understand how PST induces its anti-cancer action various biophysical techniques were employed. Neutron spin-echo (NSE) spectroscopy was used to examine …

    windsor Repository record for Mechanism Determination of the Effects of Pancratistatin on Model Mitochondrial Membranes (opens in a new tab)

  11. A scanning electron and light microscopy study of the red tide dinoflagellate Gymnodinium sp. from False Bay, South Africa

    … the north American species, which has a similar toxic effect. Ptychodiscus brevis differed from the False Bay organism in several aspects, including cell contour, the possession of an apical protrusion, and the toxins of P. brevis are lipid soluble whereas the toxins of Gymnodinium sp. are water …

    cape-town Repository record for A scanning electron and light microscopy study of the red tide dinoflagellate Gymnodinium sp. from False Bay, South Africa (opens in a new tab)

  12. An investigation into the partition functions of the broad-host-range Plasmid pTF-FC2

    … pasB gene a toxin which exerts a bacteriocidal effect in an E. coli host and the pasC gene a protein which moderates the toxic effect of PasB. The PasC is unique in proteic plasmid stabilisation systems and reduces PasB toxicity only in the presence of PasA. PasA is able to repress the pas …

    cape-town Repository record for An investigation into the partition functions of the broad-host-range Plasmid pTF-FC2 (opens in a new tab)

  13. Restoration of lowland raised bogs damaged by peat extraction - with particular emphasis on Sphagnum regeneration.

    … of CaCO3 to reduce acidity in the field had a toxic effect. 4. Sphagnum recolonisation may be limited by availability of propagules in cut-over areas. Experiments indicate that deliberate re-introduction encourages Sphagnum raft development, which is pioneered by aquatic species that regenerate …

    whiterose Repository record for Restoration of lowland raised bogs damaged by peat extraction - with particular emphasis on Sphagnum regeneration. (opens in a new tab)

  14. Combining microbial functional metagenomics and Caenorhabditis elegans genetics to uncover and characterise novel bioactive compounds

    … that target C. elegans and study their toxic effect in the nematode. Genetic and microscopic analysis uncovered known and novel bioactive compounds including the small molecules tambjamine and violacein, which appear to facilitate bacterial colonisation and induce apoptosis in the …

    unsw Repository record for Combining microbial functional metagenomics and Caenorhabditis elegans genetics to uncover and characterise novel bioactive compounds (opens in a new tab)

  15. Avaliação testicular e seminal de caprinos alimentados com feno de Cenostigma pyramidale (tul.) E. Gagnon & g. P. Lewis

    … that the consumption of C. pyramidale has no toxic effect on testicular, seminal and histological parameters of the testicle of goats, and the plant, due to its nutritional characteristics, has caused an improvement in the animals body development, and, being a plant adapted to semi-arid …

    brazil-ufba Repository record for Avaliação testicular e seminal de caprinos alimentados com feno de Cenostigma pyramidale (tul.) E. Gagnon & g. P. Lewis (opens in a new tab)

  16. Evaluation of a Microalgal Bioassay Based on Community Level Physiological Profiling (CLPP)

    … compounds (QACs) were used as potentially toxic model compounds to demonstrate the applicability of the assay. Toxicity of dodecyl trimethyl ammonium chloride (DTAC) and didecyl dimethyl ammonium bromide (DDAB) on the growth of Scenedesmus obliquus varied significantly under autotrophic, …

    uwo Repository record for Evaluation of a Microalgal Bioassay Based on Community Level Physiological Profiling (CLPP) (opens in a new tab)

  17. Acinetobacter baumannii toksino-antitoksino sistemos CheTA antitoksino veikimo mechanizmo paieška /

    … and a labile antitoxin that neutralizes the toxic effect of its cognate toxin. Under stressful conditions such as nutrient starvation or exposure to antibiotics, antitoxin is rapidly degraded allowing toxin to obstruct essential cellular processes such as DNA replication, translation or …

    vilnius Repository record for Acinetobacter baumannii toksino-antitoksino sistemos CheTA antitoksino veikimo mechanizmo paieška / (opens in a new tab)

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