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Showing 1 to 3 of 3 for “"Topoisomerase II alpha"”.
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Aktive DNS-Topoisomerase II Alpha ist eine Komponente des salzresistenten zentrosomalen Strukturgerüstes
… wir, daß der monoklonale, für die DNA-topoisomerase IIalpha spezifische Antikörper Ki-S1 nicht nur die Kerne menschlicher A431-Zellen, sondern auch extranucleäre Strukturen färbt (Meyer et. al., 1997, J. Cell. Biol. 136, 775). Diese Strukturen waren wahrscheinlich Zentrosomen. In dieser …
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Spatially mapped gene expression analysis from tissue
… and characterized a novel RT-LAMP reaction for topoisomerase II alpha (TOP2A) mRNA biomarker for LNCaP prostate cancer cells."
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The physiological role of the two isoforms of DNA topoisomerase II in human cells
Unique functions of DNA topoisomerase IIalpha and IIbeta have been suggested. A human cell line which carries a homozygeous mutation of the nuclear localization sequence of the topoisomerase IIalpha gene expresses the isoform outside the nucleus at the onset of mitosis. At mitosis topoisomerase …