Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Topiramate"”.
-
Genetic and Environmental Contributions to Baseline Cognitive Ability and Cognitive Response to Topiramate
… I assessed the effect of topiramate, an antiepileptic drug that causes marked side effects in certain cognitive areas in certain individuals, on some of the healthy volunteers (n=158) by giving them a 100 mg dose and then administering the cognitive test two hours later. I …
-
The gut microbiome: a contributing mechanism to the anti-seizure effect of topiramate
… of the commonly prescribed anti-epileptic drug topiramate on the gut microbiome. Fecal samples of mice treated with topiramate were analyzed using 16S ribosomal RNA gene sequencing. Analysis revealed that topiramate ingestion increased the probiotic bacteria Lactobacillus johnsonii in the gut …
-
The pharmacokinetics of single oral dose extended-release topiramate and adverse effects after multi-dose administration in healthy cats
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-05-01
-
Evaluation of Anti-Migraine Drugs in an in Vivo Rat Model of Chronic Migraine
… determine if two novel drugs in development and Topiramate, a common drug used to treat frequent migraine, could inhibit nocifensive responses to mechanical stimulation of trigeminal neurons. In addition, the trigeminal ganglion and STN were evaluated on a molecular level to determine if the …
-
An evaluation and comparison of current FDA-approved treatments for obesity
… extended-release, and phentermine/ topiramate extended-release became FDA-approved for long-term treatment of obesity. Each drug acts on a specific part of the CNS to modulate appetite and cause decreased food intake in patients. Clinical trials conducted on these medications found …
-
Pharmacist input into patients' self-reporting of adverse drug reactions.
… moclobemide, gabapentin, lamotrigine and topiramate from 79 participating medical practices in Grampian during January-March 1997. The overall response rates were 44.6% (n=207) for the pilot study and 36.3% (n=837) for the main study. The most frequently reported symptoms were: drowsiness …
-
Innovative analytical methods for Central Nervous System Drug analysis in biological fluids
… (aripiprazole), antiepileptics (vigabatrin and topiramate) and antiparkinsons (pramipexole). Innovative methods based on liquid chromatography or capillary electrophoresis coupled to diode-array or laser-induced fluorescence detectors have been developed, together with the suitable sample …
-
The newer anticonvulsants in the treatment of generalised anxiety disorder: a systematic review and meta-analysis
… oxcarbazepine, pregabalin, tiagabine, topiramate and zonisamide) were investigated as they were considered to have a more benign side effect profile and fewer drug interactions than older anticonvulsants. This study is a systematic review and meta-analysis of the newer anticonvulsants …