Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Tolerisation"”.
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LPS from subgingival plaque and the periodontal pathogen Porphyromonas gingivalis, its effect on M1 and M2 macrophage responses and potential as a biomarker
… following secondary stimulation (endotoxin tolerisation) suggests that mechanisms which are associated with tolerisation of M1 MΦs and both stimulation and tolerisation of M2 MΦs is due to reprogramming events conferred by a combination of TNF-α, type-I interferons and epigenetic regulation.
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Regulation of macrophage subsets in homeostatic and inflammatory mucosal environments
… and immune activation/inflammation. Endotoxin tolerisation (ET) is a circumstance where cells go through a hypo-responsive state, unable to respond to further endotoxin-LPS challenge. Mucosal macrophages (MΦs) have a dual functionality that determines tolerance to commensal organisms or immune …
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Modulation of macrophage and epithelial cell immune defences by probiotic bacteria: immune stimulation versus suppression
… STAT3 and TRAIL. Second, the repeat-stimulation/tolerisation of M1 and M2 macrophages by live probiotic bacteria revealed, TNFα, IL-1β, IL-23, IL-18, IL-6 and IL-10 were upregulated in M1-like macrophages by C28, whereas MS13 upregulated TNFα, IL-1β, IL-18, and downregulated IL-12, IL-6, and …
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Establishment of a systematised approach for the development of novel diagnostics and therapeutics in the field of biotechnology
… The immunisation according to High Zone Tolerisation led to the best results regarding a nonylphenol specific antibody titre in the mouse serum. Successful fusion of the murine B-cells with myeloma cells were performed followed by single cell sorting (FACS). Monoclonal clones could be …