Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Togaviridae"”.
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Infection and Dissemination of TaV-GFP Tagged Sindbis in Aedine Mosquitoes and Cell Lines
… arbovirus of the genus Alphavirus in the family Togaviridae. The purpose of this study was to investigate the use of a fluorescent tagged reporter virus in both in vitro and in vivo environments. The fluorescent protein GFP was inserted between the Capsid and PE2 in the genome of TR339; SINV …
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Blood-Feeding Patterns of Eastern Equine Encephalitis Virus Bridge Vectors at Viral Foci in Southeast Georgia
… is a single-stranded RNA arbovirus (family <em>Togaviridae; </em>genus <em>Alphavirus) </em>endemic to the Atlantic seaboard, southeastern United States, and parts of South America. EEEV produces particularly severe disease in incidental (dead-end) hosts such as humans and horses, with case …
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Cross-reactivity among alphaviruses provides insight into viral emergence and novel defense strategies
… viruses (arboviruses) belonging to the Togaviridae family that are maintained by mosquito vectors. These zoonotic viruses are clustered into two groups: New World and Old World, depending on their geographical origin/distribution and clinical manifestations. Both of these groups cause …
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Elucidation of antigenic epitopes on the rubella virus E1 glycoprotein
… only member of the genus Rubivirus within the Togaviridae family. The virus consists of a host derived lipid bilayer membrane, membrane glycoprotein spikes, and the C protein which together with viral RNA forms the icosahedral nucleocapsid. Although clinical rubella is a relatively mild …
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Epidemiology of Sindbis fever in South Africa and development of a real-time pan-alphavirus PCR assay for the detection of Sindbis and other medically important alphaviruses
The genus Alphavirus in the family Togaviridae consists of approximately 30 single stranded, positive-sense RNA viruses which cause diseases ranging from mild, febrile illness with rash and arthritis to life-threatening encephalitis. Sindbis virus is the prototype virus for this genus and is the …
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Evidence for RNA interference as an antiviral immune response to alphavirus infection in the mosquitoes Anopheles gambiae and Aedes aegypti
… with o'nyong-nyong virus (ONNV) (Alphavirus; Togaviridae) in An. gambiae resulted in a significant increase in viral titers and increased dissemination of the virus in those mosquitoes. Additionally, injection of the virus along with dsRNA targeting a viral gene resulted in decreased viral …
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Strucutre-function studies of the venezuelan equine encephalitis virus 5'UTR promoter element and its role in attenuation of the virus
… members of the Alphavirus genus in the Togaviridae family. VEEV \r\ninfection causes debilitating illness complicated by neurological manifestations. The \r\nonly available vaccine for VEE infection, the attenuated strain VEEV TC-83 provides \r\nminimal protection against virulent …
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The Host Response to Venezuelan Equine Encephalitis Virus
… in the Alphavirus genus in the family Togaviridae contain multiple viruses capable of causing human encephalitis. Of these, VEEV represents the most significant human pathogen. However, no licensed vaccines or therapeutics are available. A comprehensive understanding of the host …
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Modelo animal de artrite e miosite induzidas pelo vírus Mayaro
… (MAYV) pertence ao gênero Alphavirus e a família Togaviridae. Ele está incluído no grupo dos alfavírus artritogênicos, que também compreende o Vírus Ross River (RRV), Vírus Chicungunya (CHIKV) Vírus Sindbis (SINV), Vírus O’nyong-nyong (ONNV), os quais são responsáveis por causar surtos de …
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Development of Rapid Lateral-flow Immunochromatographic Test for the Diagnosis of Chikungunya Virus Infection
… Alphavirus belonging to family Togaviridae that causes a number of outbreaks in Africa, India, and Southeast Asia with high morbidity. The major clinical symptoms resulting from CHIK virus infection are high fever, arthralgia, myalgia, headache and rash, which are similarly …
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Molecular analysis of La Crosse virus transcription and replication in host cells
… with LAC virus and Sindbis (SIN) virus (family Togaviridae, genus Alphavirus) revealed interactions between unrelated viruses within the same cell, including altered growth kinetics of both viruses and differential targeting of host mRNAs. Scavenged 5' nonviral- and SIN mRNA sequences were shown …
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Adaptation of Chikungunya virus to Aedes albopictus mosquitoes: The role of mutations in the E1 AND E2 glycoproteins
… sense single-stranded RNA virus in the family Togaviridae that between 2005 and 2007 caused its largest outbreak/epidemic in documented history, affecting parts of Africa, the Indian Ocean islands, India, and Europe. An unusual feature of this epidemic was the involvement of the previously …