Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"Tissue oxygenation"”.
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Accurate noninvasive monitoring of fetal tissue oxygenation level
Fetal blood oxygenation level serves as a critical indicator of fetal health throughout pregnancy and labor. However, existing clinical devices predominantly employ invasive techniques, posing risks to both the fetus and the mother. To address this concern, we present a noninvasive method for …
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Spatiotemporal Dynamics of Tissue Oxygenation in Awake, Behaving Mice
… directly decouples neural activity-evoked oxygenation changes in the brain. These findings have important implications for interpreting data acquired by clinical neuroimaging modalities like functional magnetic resonance imaging. Understanding the relationship between neuronal activity and …
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Non-invasive objective assessment of diabetic foot ulcer healing with blood perfusion and tissue oxygenation
… examined the correlation between blood flow and tissue oxygenation in diabetic wounds. This thesis is a pioneering work that aims to develop a reliable diagnostic tool to address the tremendous need for coordinated and efficient DFU management via prediction of relative blood perfusion (τ) and …
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Oscillations in microvascular flow : their relationship to tissue oxygenation, cellular metabolic function and their diagnostic potential for detecting skin melanoma - clinical, experimental and theoretical investigations
… explored through the analysis of blood flow and oxygenation data recorded during dry static apnoea, whilst the latter is modelled using coupled phase oscillators.
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The acute response to sprint interval exercise and moderate intensity continuous exercise in adults with and without airway hyperresponsiveness
… power output). Spirometry, ventilatory measures, tissue oxygenation, and subjective responses were assessed prior to, during, and following exercise. Results: The decline in forced expiratory volume in one second was similar following SIE and MICE. Ventilatory measures, tissue oxygenation, and …
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Examining Sex Differences in Substrate Utilization During Threshold-Based Exercise Prescription
… by differences in metabolic stress and muscle oxygenation linked to sex-based differences in lactate threshold (LT) and critical power (CP). Thus, the purpose of this thesis was to examine the effect of threshold-based exercise prescribed (THR) using LT and CP to determine whether using THR – …
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Characterization and Modeling of Fluctuating Hypoxia in Breast Cancer
… potential mechanisms of fluctuations in tumor oxygenation. Using phosphorescence lifetime imaging on preclinical tumors, we show that instabilities in tumor oxygenation are a prevalent characteristic of three tumor lines and that previous characterization of tumor hypoxia as being primarily …
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Effect of workload, upper body posture, and saddle set-back on full body angular joint kinematics, muscle activity, and lower limb haemodynamics
… specific technique was developed to enable tissue oxygenation status of the lower limbs to be determined during cycling, which was then used to assess the effects of workload, trunk and hip angle, and saddle set-back on lower limb blood flow haemodynamics. It is unclear to what extent saddle …
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Injury Patterns Associated with Shock in Pediatric Trauma Patients: A National Trauma Database Review
… the development shock, or a state of poor tissue oxygenation. According to current guidelines published by the American College of Surgeons, Committee on Trauma, shock after trauma is assumed to be secondary to hemorrhage, and immediate intravascular volume replacement is instituted. …
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Tissue oxymetry using magnetic resonance spectroscopy
A noninvasive method for in vivo measurement of tissue oxygen concentration has been developed. Several techniques currently used suffer limitations that prevent their practical clinical use. Our method is to use the paramagnetism of molecular oxygen to build a method for noninvasive tissue …
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The Role of Oral Nitrate Reducing Bacteria in Cardiovascular Health: Impacts of Diet and Exercise
… Reactive hyperaemia testing indicated enhanced tissue oxygenation index (TOI) post-exercise (peak TOI: 84.8% to 86.1%; P = 0.01) in the placebo condition, a response absent with mouthwash. Overall, exercise-induced improvements in rectus femoris oxygenation were significantly blunted by …
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Non-invasive optical monitoring of free and bound oxygen in humans
… have been explored in this thesis. Perfusion and oxygenation of vital organs (e.g., heart, brain and kidneys) may be severely compromised in critical illness or major trauma, which is why blood is rapidly diverted to those organs to improve chances of survival. Blood vessels in less important …
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Investigating the effects of acute intracranial pressure and brain oxygenation on neuropsychological outcomes 12 months after severe pediatric traumatic brain injury
… changes in intracranial pressure (ICP) and brain tissue oxygenation (PbtO2) and neuropsychological outcomes one year after pTBI. Results of the study indicated that children who sustained TBI performed significantly poorer than healthy, matched controls on multiple cognitive, behavioural and …
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The Groote Schuur Hospital Neurosurgical Intensive Care Unit: A 2 Year Experience
… an intracranial pressure monitor (ICP) and brain tissue oxygenation monitor (19.3%), 86 had an external ventricular drain placed (12.5%), 50 patients required placement of a tracheostomy (7.3%) and 16 patients had only an ICP monitor placed (2.3%). The average duration of stay was 5.5 (±1.3) days …
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Intracranial Monitoring after Severe Traumatic Brain Injury
… reactivity. Cortical blood flow and brain tissue oxygenation are demonstrated to be sensitive to increases in intracranial pressure in chapter 6. In chapter 7, a method is proposed to estimate the cerebral perfusion pressure limits of reactivity in real-time, which may allow for more …
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The impact of barbiturate therapy in children with severe traumatic brain injury (TBI)
… in cerebral perfusion pressure (CPP). Brain tissue oxygenation was slightly higher on thiopentone, but not significantly. CONCLUSION: This is the largest study to analyze barbiturate therapy in children with TBI. Thiopentone was useful in decreasing ICP. Although there was an associated …
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Effekte stromafreier Hämoglobinlösungen auf die Mikrozirkulation im quergestreiften Rückenhautmuskel beim Hamster
… microvascular perfusion, oxygen delivery to the tissue is crucial for survival of the organism. For decades there was pursuit of developing oxygen carrying blood substitutes, but the breakthrough of stroma free hemoglobin solutions has failed due to different issues such as nephrotoxicity, …
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Examining the regional physiology of the transplant kidney during normothermic machine perfusion.
… Disruption to microvascular perfusion (MVP) and tissue oxygenation (PtO2) are central to the development of IRI, but detailed regional pathophysiology remains unresolved in the context of renal transplantation. Normothermic machine perfusion (NMP) is a novel preservation technology that aims to …
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Renal Blood Oxygen Level Dependent (BOLD) Magnetic Resonance Imaging with an Acute Furosemide Stimulus as a Tool to Evaluate Kidney Physiology in Patients Suspected of Renal Artery Stenosis
… utilized as a noninvasive tool to detect kidney oxygenation in a number of renal pathologic states. Specifically, it has been evaluated as a potential prognostic tool to determine which patients with severe renal artery stenosis may benefit from revascularization procedures. Currently, management …
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