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Showing 1 to 6 of 6 for “"Tissue engineered blood vessels"”.
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EVALUATION OF THE IMPORTANCE OF SMOOTH MUSCLE TO THE DEVELOPMENT OF FUNCTIONAL TISSUE ENGINEERED BLOOD VESSELS
Tissue engineered blood vessels (TBEV) represent an attractive method for developing arterial substitutes to address limitations in synthetic scaffolds and lack of suitable autologous vessels. Most studies to date have necessarily focused on incorporating endothelial cells (EC) for TEBV …
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Development and Optimization of Imaging and Image Quantification Techniques for Tissue-Engineered Blood Vessel Mimics
<p>Blood vessels mimics (BVMs) are tissue-engineered blood vessels used to test vascular devices in an environment that mimics some simple anatomical factors of native blood vessels. It is important to accurately and consistently assess tissue-engineered blood vessels, although there is currently a …
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Dynamic Non-Destructive Monitoring of Bioengineered Blood Vessel Development within a Bioreactor using Multi-Modality Imaging
Regenerative medicine involves formation of tissue or organ for replacement of a wounded or dysfunctional tissue. Healthy cells extracted from the patient are expanded and are seeded on a three-dimensional biodegradable scaffold. The structure is then placed in a bioreactor and is provided with …
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Expression, Purification, And Characterization Of Elastin-Like Polypeptides Containing Chondroitin Sulphate Binding Domains
The development of small-diameter artificial blood vessels that mimic the properties of natural blood vessels has proven to be a clinical challenge. While autologous vessels are the standard, they can be difficult to obtain and require invasive surgeries. Synthetic materials have been successful in …
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The Effects of Smooth Muscle Cells on Engineered Microvasculatures in Fibrin Hydrogels
… (from smooth muscle cells and fibroblasts in blood vessels, for example), are recruited and incorporate into the neocapillaries, and are known to mediate reciprocal interactions with ECs during angiogenesis. The overall purpose of this project is to determine how smooth muscle cells (SMCs) …
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A Tissue-Engineered Blood Vessel Model for Vascular Aging
… in isolation in vivo. The Truskey lab developed tissue-engineered blood vessels (TEBVs) which recapitulate the structure and function of an arteriole in vitro. These vessels can be fabricated rapidly, perfused immediately after fabrication, and reach functional maturity after a week. Measurements …